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wiv1 derived from fecal sample of bats was demonstrated to use bat, civet and human ace2 as receptor for cell entry.
virusi vya wiv1 viliyotolewa kwenye sampuli ya kinyesi ya popo vilionyeshwa kutumia popo, ngawa na ace2 ya binadamu kama kipokezi cha kuingia kwenye seli.
civet sars-cov has k479n and s487t mutations in its rbd, which might increase the affinity of the interaction of spike protein with human ace2 receptor.
virusi vya sars-cov vilivyo ndani ya ngawa vina mabadiliko ya k479n na s487t kwenye rbd yavyo, jambo linaloweza kuzidisha uwezekano wa mwingiliano wa protini ya s na vipokezi vya binadamu vya ace2.
in fact, only 6 amino acid residues were observed to be different from human and civet viral isolates in the rbd and 4 of them locate in the receptor-binding motif for interaction with the ace2 receptor.
hakika, ni mabaki 6 ya asidi amino pekee ndiyo yalipatikana kuwa tofauti kutoka kwa virusi vilivyotengwa kutoka kwa binadamu na ngawa kwenye rbd na 4 kati yazo ziko katika sehemu ya kuunganisha vipokezi kwa ajili ya miingiliano na kipokezi cha ace2.
the rbd of sars-cov is capable of recognizing the ace2 receptors of various animals, including bat, civet, mouse and raccoon dog, allowing interspecies transmission of the virus.
rbd ya sars-cov ina uwezo wa kutambua vipokezi vya ace2 vya wanyama mbalimbali, ikiwa ni pamoja na popo, ngawa, panya na mbwa, na kuruhusu usambazaji wa virusi baina ya viumbe.
based on the comparative analysis between isolates of human and civet sars-covs, sars-cov is thought to undergo rapid adaptation in different hosts, particularly with mutations at the rbd of the s protein.
kulingana na uchanganuzi wa kiulinganisho kati ya sars-cov ndani ya binadamu na ngawa, sars-cov inadhaniwa kuzoeleka haraka ndani ya wabebaji tofauti, hasa kwa mabadiliko katika rbd ya protini ya s.
given that sars-cov infection originates from the contact between humans and civets in the markets, closing wet markets and killing civets therein could have effectively ended the sars epidemic.
kwa kuwa maambukizi ya sars-cov hutokana na kutangamana kati ya binadamu na ngawa sokoni, kufunga soko za wanyama na kuwauwa ngawa wote mle kungesaidia kungefanikiwa kukomesha janga la sars.