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saquinavir inducerer ikke kromosomale skader in vivo i en mikronukleus- test på mus eller in vitro i humane perifere blodlymfocytter.
saquinavir does not induce chromosomal damage in vivo in the mouse micronucleus assay or in vitro in human peripheral blood lymphocytes and does not induce primary dna damage in vitro in the unscheduled dna synthesis test.
Dernière mise à jour : 2011-10-23
Fréquence d'utilisation : 1
Qualité :
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herudover viste perifere blodlymfocytter intet signifikant fald i antal eller i proliferativt respons af in vitro mitogenisk stimulation sammenlignet med ubehandlede patienters celler.
peripheral blood lymphocytes further showed no significant decrease in number or in proliferative responses to in vitro mitogenic stimulation when compared with untreated patients’ cells.
Dernière mise à jour : 2017-04-26
Fréquence d'utilisation : 2
Qualité :
cidofovir inducerede kromosomafvigelser i humane perifere blodlymfocytter in vitro uden metabolisk aktivering (s- 9 fraktion).
cidofovir induced chromosomal aberrations in human peripheral blood lymphocytes in vitro without metabolic activation (s-9 fraction).
Dernière mise à jour : 2017-04-26
Fréquence d'utilisation : 2
Qualité :
boceprevir var ikke genotoksisk i en række in vitro- og in vivo-tests, herunder tests for bakteriel mutagenicitet, perifere humane blodlymfocytter og mikronukleærtest hos mus.
boceprevir was not genotoxic in a battery of in vitro or in vivo assays, including bacterial mutagenicity, human peripheral blood lymphocyte and mouse micronucleus assays.
Dernière mise à jour : 2017-04-26
Fréquence d'utilisation : 1
Qualité :
der blev ikke iagttaget nogen virkning af ammonieret karamel med 23 og 143 mg thi/kg på antallet af blodlymfocytter (i alt og i undergrupper) eller på proliferative reaktioner på mitogen stimulation.
no effect of the intake of ammonia caramel with 23 and 143 mg of thi/kg were observed on blood lymphocyte numbers (total and within subsets) or on proliferative responses to mitogenic stimulation.
Dernière mise à jour : 2014-02-06
Fréquence d'utilisation : 1
Qualité :
idelalisib inducerede ikke mutationer i den mikrobielle mutagenese (ames)-analyse, det var ikke klastogent i in vitro kromosomsaberrationsanalysen med humane perifere blodlymfocytter, og det var ikke genotoksisk i in vivo rotte mikronukleusstudiet.
idelalisib did not induce mutations in the microbial mutagenesis (ames) assay, was not clastogenic in the in vitro chromosome aberration assay using human peripheral blood lymphocytes, and was not genotoxic in the in vivo rat micronucleus study.
Dernière mise à jour : 2017-04-26
Fréquence d'utilisation : 1
Qualité :
amprenavirs antivirale in vitro-aktivitet blev evalueret over for hiv-1-iiib i både akut og kronisk inficerede lymfoblastiske cellelinier (mt-4, cem-ccrf, h9) og perifere blodlymfocytter.
the in vitro antiviral activity of amprenavir was evaluated against hiv-1 iiib in both acutely and chronically infected lymphoblastic cell lines (mt-4, cem-ccrf, h9) and in peripheral blood lymphocytes.
Dernière mise à jour : 2017-04-26
Fréquence d'utilisation : 7
Qualité :