Vous avez cherché: bijotrasformat (Maltais - Anglais)

clopidogrel irid jiġi bijotrasformat biex jinibixxi l- aggregazzjoni tal- plejtlets.
biotransformation of clopidogrel is necessary to produce inhibition of platelet aggregation.

studji in vitro u in vivo jindikaw li venlafaxine jiġi bijotrasformat għal metabolit attiv maġġuri tiegħu, odv, minn cyp2d6.
in vitro and in vivo studies indicate that venlafaxine is biotransformed to its major active metabolite, odv, by cyp2d6.

valsartan ma jiġix bijotrasformat b’ mod estensiv peress li madwar 20% biss tad- doża hija rkuprata bħala metaboliti.
valsartan is not biotransformed to a high extent as only about 20% of dose is recovered as metabolites.

il-mod primarju jinvolvi enżim li huwa marbut ma’ cytosolic nadp+, ghb dehydrogenase, li jikkataliżża l-konverżjoni ta’ sodium oxybate f’ succinic semialdehyde, li huwa imbagħad bijotrasformat f’ succinic acid bl’ enżim succinic semialdehyde dehydrogenase.
the primary pathway involves a cytosolic nadp+-linked enzyme, ghb dehydrogenase, that catalyses the conversion of sodium oxybate to succinic semialdehyde, which is then biotransformed to succinic acid by the enzyme succinic semialdehyde dehydrogenase.