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en minimal grad af inflammation og/eller mononukleær celleinfiltration blev set i flere organer.
a minimal grade of inflammation and/or mononuclear cell infiltration was seen in several organs.
Ultimo aggiornamento 2017-04-26
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det bløde væv i nærheden af injektionsstedet havde fibroplasmia ledsaget af mononuclear celleinfiltration, som afspejler pdgfs evne til at stimulere væksten af bindevæv.
the soft tissue adjacent to the injection site had fibroplasia with accompanying mononuclear cell infiltration reflective of the ability of pdgf to stimulate connective tissue growth.
Ultimo aggiornamento 2017-04-26
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i det bageste segment var der vitreal celleinfiltration og mouches volantes, som også havde tendens til at være dosisafhængige, og de varede generelt ved til udgangen af behandlingsperioden.
in the posterior segment, there were vitreal cell infiltration and floaters, which also tended to be dose-dependent and generally persisted to the end of the treatment period.
Ultimo aggiornamento 2017-04-26
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egfr-signalbaner er involverede i kontrollen af cellernes overlevelse, udvikling i cellecyklus, angiogenese, cellemigration og celleinfiltration/metastaser.
egfr signalling pathways are involved in the control of cell survival, cell cycle progression, angiogenesis, cell migration and cellular invasion/metastasis.
Ultimo aggiornamento 2017-04-26
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i kliniske studier hos patienter med psoriasis reducerede apremilast epidermis-fortykkelse af hudlæsionerne, inflammatorisk celleinfiltration og ekspressionen af proinflammatoriske gener, herunder generne for inducerbart nitrogenoxidsyntase (inos), il-12/il- 23p40, il-17a, il-22 og il-8.
in clinical trials in patients with psoriasis, apremilast decreased lesional skin epidermal thickness, inflammatory cell infiltration, and expression of pro-inflammatory genes, including those for inducible nitric oxide synthase (inos), il-12/il-23p40, il-17a, il-22 and il-8.
Ultimo aggiornamento 2017-04-26
Frequenza di utilizzo: 1
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