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la présente invention concerne un procédé de production de mannite présentant une proportion de modification α supérieure à 90 %, qui peut être directement mise sous forme de comprimés.
the invention relates to a method for producing mannite which has an α modification content of more than 90 % and is directly compressible into tablets. the inventive method is characterized by the following steps: a) an aqueous d mannite solution is combined with spray gas, powdered α mannite, and hot gas. air or an inert gas selected from the group n2 and co2 is used both as a spray gas and as a carrier gas and heating gas; b) the resulting powdered product falls into a fluid bed or fixed bed, is absorbed, fluidized, and redirected; c) a partial quantity of the resulting powdered product is returned to the process; and optionally d) the resulting powder is sprayed with an additional fluid medium, dried, and redirected in a fixed bed or fluid bed in one or several granulation step(s).
le ligand phosphinique dans le système de catalyseur est un ligand chiral d'ester de phosphite hautement actif, obtenu par la réaction de sources chirales de d-mannite ou l-mannite
the phosphine ligand in this catalyst system was a highly active chiral phosphite ester ligand, which was obtained by the reaction of chiral d-mannite or l-mannite chiral sources
procédé de préparation d'un mélange de alpha-d-glucopyranosido-1,6-mannite et alpha-d-glucopyranosido-1,6-sorbite à partir de alpha-d-glucopyranosido-1,6-fructose.
process for the production of a mixture of alpha-d-glycopyranosido-1,6-mannite and alpha-d-glycopyranosido-1,6-sorbite from alpha-d-glycopyranosido-1,6-fructose.
