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it's pleomorphic, but tends toward ovoid in shape. i see structures on the surface that look like glycoproteins but there's nothing morphologically pathognomonic.
إنّه متعدد الأشكال، لكنّه يميل نحو الشكل البيضوي، أرى هياكل على السطح تبدو مثل "جليكوبروتينات"...
major biopsy: excision histopath no _ hp 3212/15 nature of specimen - a) lateral left breast lesion. b) periareolar left breast lesion. clinical details - lateral breast lesion tru-cut biopsy. periareolar lesion pain and palpable mass at left breast only since 1 month. ultrasound/mamography showed 2 palpable masses, 1 lateral and second periareolar bi-rads v. suspected breast mass. gross observation - received 2 containers : a) container labelled (lateral lesion) contains 4 grey white tissue cores ms 0.4-1.5x0.l cm. all tissue processed. b) container laballed (periareolar lesion) contains 4-5 grey white tissue cores ms 0.5-2x0.1cm. all tissue processed. microscopic findings i a) serial sections demonstrate four needle cores from the breast two of them almost completely iniilltrated by neoplastic cells with obvious cytological features of malignancy arranged in cords and linear files some indian file pattern with intervening demoplastic collagenous stroma. the constituent cells exhibit pleomorphic hyperchromatic nuclei with irregular nuclear chromation and many intracellular lumina. elsewhere most of the lobular units in other cores reveal lobular carcinoma in situ (lcis) as well as transition from lcis to invasive in one fragment. no evidence of dcis or lymphovascular invasion seen. no micro calcitications noted. b) sections consits of breast parenchyma formed of normal lobular units and surrounding iibrofatty tissue. no evidence of neoplasia seen. impression l a) left lateral breast lesion, core needle biopsy - invasive lobular carcinoma, pleomorphic variant grade 2 (elston scheme) with multiple foci of lcis. * no lymphovascular invasion present. * no microcalcitications seen. b) left periareolar lesion, core needle biopsy - benign breast tissue. negative for neoplasia. recommendation - utilization of immunostains e.cadherin and p63 will be more reassuring in the tumor detected in (a).
مجانية على الانترنت القاموس الطبي engilsh إلى العربية
Ultimo aggiornamento 2015-11-02
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