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ph
ph
Ultimo aggiornamento 2020-09-27
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as seen in fig. 5, the degradation rate constant of col 3 increases in a non linear manner as ph increases. the ph of maximum stability is below ph 4. the degradation rate increases with ph between 3 and 6, reaching a plateau between about ph 6 and 7, after which the rate increases again until minimum stability is observed above ph 10. this shape of the profile suggests that the dissociation equilibrium of the drug and the hydroxide ion concentration are the major factors, which influence the de
seperti yang terlihat pada gambar. 5, konstanta laju degradasi col 3 meningkat secara non linier dengan meningkatnya ph. ph stabilitas maksimum di bawah ph 4. laju degradasi meningkat dengan ph antara 3 dan 6, mencapai dataran tinggi antara sekitar ph 6 dan 7, setelah itu laju meningkat lagi sampai stabilitas minimum diamati di atas ph 10. bentuk profil menunjukkan bahwa kesetimbangan disosiasi obat dan konsentrasi ion hidroksida adalah faktor utama, yang mempengaruhi de
Ultimo aggiornamento 2020-10-12
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