Hai cercato la traduzione di demethylation da Inglese a Islandese

the major route of biotransformation of clomipramine is demethylation to desmethylclomipramine.
helsta umbrotsleið clomipramins er methylsvipting sem leiðir til myndunar desmethylclomipramins.

sirolimus is extensively metabolised by o-demethylation and/or hydroxylation.
sirolimus umbrotnar verulega við o-demetyleringu og/eða hydroxyleringu.

the main metabolic pathway, n-demethylation, is mediated mainly by cyp3a.
aðalumbrota- leiðin, n-metýlsvipting, verður einkum fyrir tilstilli cyp 3a.

n-dealkylation, o-demethylation, oxidation and partial loss of the peg chain.
n-dealkyleringu, o-demethyleringu, oxun og missi peg keðju að hluta til.

o-demethylation and hydroxylation at the 3-oxopiperidinyl moiety are the major sites of biotransformation.
helstu leiðir umbrots eru o-metýlsvipting og hydroxýltenging við 3-oxopiperidiny hlutann.

fourteen primary pathways have been identified of which o-demethylation and n-dealkylation are the most important.
fjórtán meginefnaferli hafa greinst og af þeim er o-afmetýlering og n-afalkýlering mikilvægust.

metabolites identified in faeces were formed via oxidation at the macrocyclic moiety or aromatic moiety or both and by o-demethylation followed by oxidation.
umbrotsefni sem greindust í hægðum mynduðust með oxun á hringhluta (macrocyclic eða aromatic hluta) eða hvort tveggja og með o-afmetýleringu og síðan oxun.

n-demethylation of methylnaltrexone bromide to produce naltrexone is not significant, accounting for 0.06 % of the administered dose.
n-demetýlering á metýlnaltrexónbrómíði til myndunar naltrexóns er mjög lítil, eða sem svarar 0,06 % af gefnum skammti.

approximately 2% of the afatinib dose was metabolized by fmo3 and the cyp3a4-dependent n-demethylation was too low to be quantitatively detected.
um það bil 2% skammts af afatinibi voru umbrotin af fmo3 og cyp3a4-háð n-afmetýlering var of lítil til að hægt væri að greina hana.

the primary mode of action of voriconazole is the inhibition of fungal cytochrome p450-mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis.
aðal verkunarháttur vórikónazóls er hindrun afmetýleringar 14-lanósteróls af völdum cýtókróms p450, en það er nauðsynlegt skref í framleiðslu ergósteróls hjá sveppum.

direct glucuronidation (mediated by ugt1a4) and cytochrome p450 (primarily cyp1a2, with contributions of 2d6 and 3a4) mediated oxidation and demethylation are the primary metabolic pathways for asenapine.
aðalumbrotsferlar asenapins eru bein glúkúróníðtenging (fyrir tilstilli ugt1a4) og oxun fyrir tilstilli cýtókróm p450 (aðallega cyp1a2 en að einhverju leyti einnig 2d6 og 3a4) og metýlsvipting.