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the in vitro mammalian cell gene mutation test can be used to detect gene mutations induced by chemical substances.
preizkus genskih mutacij v celicah sesalcev in vitro se lahko uporablja za odkrivanje genskih mutacij, ki jih povzročajo kemične snovi.
quantitative differences are due to an additional class of mutations at the autosomal tk locus, mutation res., 216, pp. 9-17.
quantitative differences are due to an additional class of mutations at the autosomal tk locus, mutation res., 216, str. 9-17.
on the other hand, factors which enhance the sensitivity of the bacterial reverse mutation test can lead to an overestimation of mutagenic activity.
po drugi strani pa lahko dejavniki, ki povečajo občutljivost preizkusa bakterijskih povratnih mutacij, privedejo do precenitve mutagenega delovanja.
an in vitro test for gene mutations in bacteria, an in vitro cytogenicity test in mammalian cells and an in vitro gene mutation test in mammalian cells are required
izvesti je treba preskus genskih mutacij in vitro na bakterijah, citogenetski preskus in vitro na celicah sesalcev in preskus genskih mutacij in vitro na celicah sesalcev,
all patients were required to have egfr t790m mutation-positive nsclc identified by the cobas egfr mutation test performed in a central laboratory prior to treatment.
vsi bolniki so morali imeti nsclc, pozitiven za mutacijo t790m egfr, ugotovljen s testom cobas za odkrivanje mutacij egfr, opravljenim v centralnem laboratoriju pred začetkom zdravljenja.
the bacterial reverse mutation test is commonly employed as an initial screen for genotoxic activity and, in particular, for point mutation-inducing activity.
preizkus bakterijskih povratnih mutacij se splošno uporablja kot začetno presejanje za odkrivanje genotoksičnega delovanja in zlasti delovanja, ki povzroči točkovne mutacije.
the bacterial reverse mutation test utilises prokaryotic cells, which differ from mammalian cells in such factors as uptake, metabolism, chromosome structure and dna repair processes.
pri preizkusu bakterijskih povratnih mutacij se uporabljajo prokariontske celice, ki se od sesalskih razlikujejo v lastnostih, kakor so sprejemanje, presnova, kromsomska struktura in procesi popravljanja dna.
olanzapine was not mutagenic or clastogenic in a full range of standard tests, which included bacterial mutation tests and in vitro and in vivo mammalian tests.
olanzapin ni bil mutagen ali klastogen v širokem razponu standardnih testov, ki je vključeval teste mutiranja bakterij ter in vitro in in vivo teste na sesalcih.
13 olanzapine was not mutagenic or clastogenic in a full range of standard tests, which included bacterial mutation tests and in vitro and in vivo mammalian tests.
mutagenost olanzapin ni bil mutagen ali klastogen v širokem razponu standardnih testov, ki je vključeval teste mutiranja bakterij ter in vitro in in vivo teste na sesalcih.