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patient under investigation
ผู้ป่วยเข้าเกณฑ์สงสัยต้องเฝ้าระวัง
Ultimo aggiornamento 2020-05-09
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anti-sd was first produced by mrs dreyer, a caucasian south african, and the second case was with mrs b-c (ethnicity not reported).6,10 the antibody in mrs b-c's case was initially reported recognizing an antigen on the rh-associated glycoprotein (rhag) molecule. however, subsequent investigations determined that the antibody was anti-sd.10,11 anti-sd reacts strongly in the indirect antiglobulin test (iat). to our knowledge, these two cases are the only clinical reports that involved anti- sd in pregnancy. in both cases, anti-sd antibody caused severe hemolytic disease of the fetus and newborn (hdfn) in their second-born child but not first-born.6,10
แอนติเจนของกลุ่มเลือด mns ดําเนินการกับ glycophorin a (gpa), glycophorin b (gpb) หรือลูกผสมของ gpa/gpb gpb เข้ารหัสโดยยีน gypb แสดงแอนติเจนที่มีความชุกสูง 'n', u, jenu และแอนติเจนโพลีมอร์ฟิก s และ s พื้นฐานทางพันธุกรรมสําหรับแอนติเจน s คือ gypb c.143c (p.thr48)