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de belangrijkste biotransformatieroute van clomipramine is de demethylatie tot desmethylclomipramine.
the major route of biotransformation of clomipramine is demethylation to desmethylclomipramine.
Ultimo aggiornamento 2017-04-26
Frequenza di utilizzo: 3
Qualità:
kinidine verhoogt de plasmaspiegels van dextromethorfan door competitieve remming van cytochroom p450 2d6 (cyp2d6), dat een belangrijke biotransformatieroute voor dextromethorfan katalyseert.
quinidine increases plasma levels of dextromethorphan by competitively inhibiting cytochrome p450 2d6 (cyp2d6), which catalyses a major biotransformation pathway for dextromethorphan.
Ultimo aggiornamento 2017-04-26
Frequenza di utilizzo: 1
Qualità:
de biotransformatierouten zijn net als de metabolieten niet volledig beschreven.
the biotransformation pathways as well as the metabolites are not fully characterised.
Ultimo aggiornamento 2017-04-26
Frequenza di utilizzo: 3
Qualità:
