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maternični adenokarcinom epigenetskega izvora bi lahko bil povezan z indukcijo encima iz družine cyp1.
uterine adenocarcinomas, of epigenetic origin, could be related to an enzyme induction of cyp1 family.
dolgotrajno zdravljenje samo z estrogeni lahko poveča tveganje za raka na maternični sluznici (raka na endometriju).
treatment with unopposed oestrogens for long periods of time also increases the risk of cancer of the lining of the womb (endometrial cancer).
pojavnost sprememb na maternični sluznici je bila nekoliko večja kot pri sočasnih kontrolah, vendar pa znotraj osnovnih meja za samice podgan.
the incidence of endometrial findings was slightly increased over concurrent controls, but within background range for female rats.
pri jemanju zdravila fycompa uporabljajte druge oblike varne in učinkovite kontracepcije (npr. kondom ali maternični vložek).
you should use other forms of safe and effective contraception (such as a condom or coil) when taking fycompa.
vgnezditev (nidacija): pritrditev blastociste v epitelno maternično sluznico, vključno s prediranjem skozi maternični epitelij in vsaditvijo v endometrij.
implantation (nidation): attachment of the blastocyst to the epithelial lining of the uterus, including its penetration through the uterine epithelium, and its embedding in the endometrium.
te bolezni vključujejo rak materničnega vratu, predrakave spremembe na ženskih spolovilih (maternični vrat, vulva in nožnica) in bradavice na spolovilih.
hpv types 16 and 18 are responsible for ~70% of cervical cancer cases and 70% of hpv-related pre-cancerous lesions of the vulva and vagina.
pomen adenokarcinomov na maternični sluznici za človeka ni pojasnjen, vendar pa med kliničnimi preskušanji ali med uporabo zdravila po pridobitvi dovoljenja za promet ni bilo znakov, ki bi kazali, da imajo te ugotovitve klinični pomen.
the relevance of the uterine endometrial adenocarcinomas for humans is uncertain; however there is no evidence from clinical trials or marketed use to suggest that these findings are of clinical significance.
med te bolezni spadajo predrakave spremembe in rak na ženskih spolovilih (maternični vrat, vulva in nožnica), predrakave spremembe in rak zadnjika ter bradavice na spolovilih pri moških in ženskah.
these diseases include pre-cancerous lesions and cancers of the female genitals (cervix, vulva, and vagina), pre-cancerous lesions and cancers of the anus and genital warts in males and females.
cistokela, bolezni endometrija, hipertrofija endometrija* (ultrazvočno ugotovljena zadebelitev endometrija), maternični polip, izcedek iz nožnice, bolezni nožnice
cystocele, endometrial disorder, endometrial hypertrophy* (sonographic endometrial thickness), uterine polyp, vaginal discharge, vaginal disorder
le pri podganah so pri samcih pri izpostavljenosti, ki je ustrezala 0,5-kratni izpostavljenosti pri človeku, ugotovili večjo pojavnost hiperplazije intersticijskih celic, pri samicah pa pri izpostavljenosti, ki je ustrezala 1,1-kratni izpostavljenosti pri človeku, večjo pojavnost adenokarcinomov na maternični sluznici.
in rats only there was an increase in interstitial cell hyperplasia in males at exposure levels equivalent to 0.5- fold those in humans, and an increase in uterine endometrial adenocarcinoma in females at an exposure level equivalent to 1.1-fold those in humans.