検索ワード: kromosom (スロベニア語 - 英語)

kromosom
chromosome

endoredupliciran kromosom
endoreduplicated chromosome

invertiran x-kromosom
inverted x-chromosome

bolniki, pozitivni na kromosom philadelphia
philadelphia chromosome-positive patients

kromosom je organizirana struktura, ki vsebuje dnk in histone.
the set of chromosomes in a cell and any other hereditary information found in the mitochondria, chloroplasts, or other locations is collectively known as its genome.

kromosom x predstavlja približno eno petino celotnega haploidnega genoma.
the x-chromosome represents approximately one-fifth of the entire haploid genome.

kromosom philadelphia je prisoten pri vseh bolnikih z all in pri večini bolnikov s kml.
the philadelphia-chromosome is found in some all patients and is present in most patients with cml.

varnosti in učinkovitosti zdravila spectrila pri bolnikih, pozitivnih na kromosom philadelphia, niso dokazali.
efficacy and safety of spectrila have not been established in philadelphia chromosome-positive patients.

ta kromosom proizvaja encim, imenovan bcr-abl kinaza, ki povzroča razvoj levkemije.
this chromosome produces an enzyme, called bcr-abl kinase, that leads to the development of leukaemia.

fabryjeva bolezen je napredujoča na kromosom x vezana motnja lizosomskega skladiščenja, ki prizadene moške in ženske.
fabry disease is a progressive x-linked lysosomal storage disorder which affects males and females.

zdravilo bosulif se uporablja pri bolnikih, pri katerih je prisoten kromosom philadelphia (ph+).
bosulif is used in patients who are ‘philadelphia-chromosome positive’ (ph+).

to pomeni, da je prišlo do prerazporeditve nekaterih genov, s čimer je nastal poseben kromosom, imenovan kromosom philadelphia.
this means that some of their genes have re-arranged themselves to form a special chromosome called the philadelphia chromosome.

to pomeni, da je pri njih prišlo do prerazporeditve nekaterih genov, s čimer je nastal poseben kromosom, imenovan kromosom philadelphia.
this means that some of their genes have re-arranged themselves to form a special chromosome called the philadelphia chromosome.

ph+ pomeni, da so se geni nekaterih bolnikov prerazporedili tako, da tvorijo poseben kromosom, ki se imenuje kromosom philadelphia.
ph+ means that some of the patient’s genes have rearranged themselves to form a special chromosome called the philadelphia chromosome which produces an enzyme, bcr-abl kinase, that leads to the development of leukaemia.

pri tej vrsti levkemije se je del dnk (genetski material) prerazporedil in oblikoval nenormalen kromosom, ki se imenuje kromosom philadelphia.
in this kind of leukaemia, some of the dna (genetic material) has become rearranged to form an abnormal chromosome, the philadelphia chromosome.

poliploidija številčne kromosomske aberacije v celicah ali organizmih, ki ne vplivajo na posamezen kromosom ali kromosome (anevploidija), ampak na vse kromosome.
polyploidy numerical chromosome aberrations in cells or organisms involving entire set(s) of chromosomes, as opposed to an individual chromosome or chromosomes (aneuploidy).

hemofilija a je na spolni kromosom vezana dedna motnja strjevanja krvi zaradi znižane ravni fviii in posledica so obsežne krvavitve v sklepe, mišice ali notranje organe, bodisi spontano bodisi kot posledice nezgod ali kirurških poškodb.
haemophilia a is a sex-linked hereditary disorder of blood coagulation due to decreased levels of fviii and results in profuse bleeding into joints, muscles or internal organs, either spontaneously or as a result of accidental or surgical trauma.

uporablja se pri bolnikih s prisotnim kromosomom philadelphia (ph+), kar pomeni, da so se nekateri bolnikovi geni preuredili in tvorijo poseben kromosom, imenovan kromosom philadelphia.
it is used when the patient is ‘philadelphia chromosome positive’ (ph+), which means that some of the patient’s genes have re-arranged themselves to form a special chromosome called the philadelphia chromosome.

v vseh študijah so odziv bolnikov ocenjevali z merjenjem količine belih krvnih celic in trombocitov v krvi, da bi ugotovili ali so se te vrnile na normalne ravni, in merjenjem deleža belih krvnih celic, ki vsebujejo kromosom philadelphia, da bi ugotovili ali se je ta znižal.
all of the studies assessed the patients’ responses by measuring the amount of white cells and platelets in the blood, to see if they were returning to normal levels, and the proportion of the patients’ white blood cells that contained the philadelphia chromosome, to see if it was decreasing.

zdravilo sprycel se uporablja pri bolnikih, ki ne prenašajo drugih načinov zdravljenja, vključno z imatinibom (drugim zdravilom proti raku), ali pa se nanje ne odzivajo; • uporablja se tudi pri akutni limfoblastni levkemiji (all), vrsti levkemije, pri kateri se limfociti (še ena vrsta belih krvnih celic) razmnožujejo prehitro, ali pri kml v fazi blastne preobrazbe, v kateri so bolniki „ pozitivni na kromosom philadelphia “ (ph+).
sprycel is used when patients cannot tolerate, or when their disease is not responding to other treatments including imatinib (another anticancer medicine); • it is also used in acute lymphoblastic leukaemia (all), a type of leukaemia where lymphocytes (another type of white blood cell) multiply too quickly, or blast phase cml, when the patients are ‘ philadelphia chromosome positive ’ (ph+).