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cmax: ↓ 34% (↓ 21 għal ↓ 47) hydroxybupropion:
cmax: ↓ 34% (↓ 21 to ↓ 47) hydroxybupropion:
最終更新: 2017-04-26
使用頻度: 1
品質:
bupropion jiġi metabolizzat għal metabolit attiv ewlieni tiegħu hydroxybupropion prinċipalment bl- isoenzina cyp2b6.
bupropion is metabolised to its major active metabolite hydroxybupropion primarily by the cyp2b6 isozyme.
最終更新: 2017-04-26
使用頻度: 1
品質:
bupropion huwa metabolizzat b’mod estensiv bi tliet metaboliti attivi: hydroxybupropion, threohydrobupropion u erythrohydrobupropion.
bupropion is extensively metabolised with three active metabolites: hydroxybupropion, threohydrobupropion and erythrohydrobupropion.
最終更新: 2017-04-26
使用頻度: 1
品質:
bupropion: f’ voluntiera f’ saħħithom, l- auc u c max ta ’ bupropion u tal- metabolit attiv tiegħu, hydroxybupropion, naqsu b’ madwar 50% meta ngħataw flimkien ma ’ kapsuli lopinavir/ ritonavir ta ’ 400/ 100 mg darbtejn kuljum fi stat fiss.
8 bupropion: in healthy volunteers, the auc and cmax of bupropion and of its active metabolite, hydroxybupropion, were decreased by about 50% when co-administered with lopinavir/ ritonavir capsules 400/ 100 mg twice daily at steady-state.
最終更新: 2012-04-10
使用頻度: 3
品質: