검색어: biotransformacijo (슬로베니아어 - 영어)

sopomenka za ‚biotransformacijo‘.
synonymous with “biotransformation”.

v glavnem z biotransformacijo.
there is no clinical experience with massive overdose.

midazolam se skoraj v celoti izloča z biotransformacijo.
midazolam is almost entirely eliminated by biotransformation.

več izoencimov sistema cyp je vpletenih v oksidativno biotransformacijo glikopironija.
multiple cyp isoenzymes contribute to the oxidative biotransformation of glycopyrronium.

ugotovljeno je, da je v biotransformacijo glimepirida v m1 vpleten cyp2c9.
cyp2c9 has been shown to be involved in the biotransformation of glimepiride to m1.

cyp2d15 in cyp3a12 sta pasji izoformi, vključeni v biotransformacijo maropitanta v jetrih.
cyp2d15 and cyp3a12 were identified as the canine isoforms involved in the hepatic biotransformation of maropitant.

presnova glimepirid se tako po intravenski kot po peroralni uporabi povsem presnovi z oksidativno biotransformacijo.
metabolism glimepiride is completely metabolised by oxidative biotransformation after either an intravenous or oral dose.

Študije in vitro in in vivo kažejo, da ritonavir močno zavira biotransformacijo s cyp3a in cyp2d6.
in vitro and in vivo studies have demonstrated that ritonavir is a potent inhibitor of cyp3a- and cyp2d6- mediated biotransformations.

15 raziskovali, je možnost le- teh majhna, ker se antiholinergiki izločajo v glavnem z biotransformacijo.
as anticholinergics are mainly eliminated by biotransformation, the potential for an interaction is limited, although an interaction with anticholinergics has not been investigated.

po intravenski uporabi se 47 % odmerka izloči prek ledvic, 53 % pa biliarno in z biotransformacijo.
after intravenous administration, 47% of the dose is eliminated by the renal excretion and 53% by biliary excretion and biotransformation.

rezultati in vitro so pokazali, da je pri človeku poglavitni encim p450, ki katalizira biotransformacijo imatiniba, cyp3a4.
the in vitro results showed that cyp3a4 was the major human p450 enzyme catalysing the biotransformation of imatinib.

zato so interakcije z drugimi zdravili, ki bi vplivale na vezavo na plazemske proteine ali na izločanje z biotransformacijo, malo verjetne.
therefore, interactions with other medicinal products affecting plasma protein binding or elimination by biotransformation are unlikely.

Čeprav interakcij z antiholinergiki niso raziskovali, je možnost le-teh majhna, ker se antiholinergiki izločajo v glavnem z biotransformacijo.
as anticholinergics are mainly eliminated by biotransformation, the potential for an interaction is limited, although an interaction with anticholinergics has not been investigated.

ker pri bolnikih niso odkrili biološko pomembnih ravni betulina, nadaljnjih študij, povezanih s porazdelitvijo, biotransformacijo in izločanjem, niso izvedli.
since no biologically relevant levels of betulin were found in patients, no further studies related to distribution, biotransformation and elimination were performed.

fingolimod se izloča z oksidativno biotransformacijo, ki jo katalizira pretežno izoencim cyp4f2 in verjetno ostali izoencimi, nato pa z degradacijo kot pri maščobnih kislinah na neaktivne metabolite.
fingolimod is eliminated by oxidative biotransformation catalysed mainly via cyp4f2 and possibly other isoenzymes and subsequent fatty acid-like degradation to inactive metabolites.

in vivo je bilo dokazano, da zdravilo kaletra inducira svojo lastno presnovo in zvečuje biotransformacijo nekaterih zdravil, ki se presnavljajo z encimi citokroma p450 (vključno s cyp2c9 in cyp2c19) in z glukuronidacijo.
kaletra has been shown in vivo to induce its own metabolism and to increase the biotransformation of some medicinal products metabolised by cytochrome p450 enzymes (including cyp2c9 and cyp2c19) and by glucuronidation.

amidaze, ki so prisotne v krvi, plazmi, serumu, simuliranem želodčnem soku in simuliranem črevesnem soku, in človeške karboksilesteraze hce-1 in hce-2 niso odgovorne za biotransformacijo safinamida v nw-1153.
amidase present in blood, plasma, serum, simulated gastric fluid and simulated intestinal fluid as well as human carboxylesterases hce-1 and hce-2 are not responsible for the biotransformation of safinamide to nw-1153.