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cyp2a6*4 alleles are the whole deleted type and are completely deficient in the enzymatic activity. an unequal crossover junction is located in the 30 -flanking region in the cyp2a6*4a allele, whereas the junction is located in either intron 8 or exon 9 in the cyp2a6*4d allele. in the present study, a novel genotyping method to distinguish between two different whole deleted alleles of cyp2a6*4a and cyp2a6*4d was established. in the process, two novel alleles, cyp2a6*1f and cyp2a6*1g, were found.
persimpangan crossover yang tidak sama terletak di wilayah 30 mengapit di alel cyp2a6*4a, sedangkan persimpangan terletak di intron 8 atau exon 9 di alel cyp2a6*4d. dalam penelitian ini, metode genotipe baru untuk membedakan antara dua alel yang dihapus secara keseluruhan yang berbeda dari cyp2a6 * 4a dan cyp2a6 * 4d didirikan. dalam prosesnya, dua alel baru, cyp2a6*1f dan cyp2a6*1g, ditemukan
마지막 업데이트: 2022-12-01
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