검색어: alghetkel (에스토니아어 - 영어)

viroloogilisi uuringuid viidi läbi alghetkel ning 6 kuu ja 12 kuu järel.
virologic evaluations were performed at baseline, six months and 12 months.

tunnuste mediaanväärtused alghetkel olid: vanus 41 aastat, haiguse kestus 8,9 aastat, edss skoor 2,5.
median values for baseline characteristics were: age 41 years, disease duration 8.9 years, edss score 2.5.

alghetkel leiti viis fenotüüpset nevirapiini resistentsuse juhtu; ic50 väärtused olid 5 kuni 6, 5 korda tõusnud kolmel juhul ja rohkem kui 100 korda kahel juhul.
at baseline, there were five cases of phenotypic resistance to nevirapine; the ic50 values were 5 to 6.5-fold increased in three and > 100 fold in two.

mrt rühma lisatud patsientidest 36%-l olid alghetkel gd+ kolded (keskmine gd+ kollete arv 1,4).
in the mri cohort 36% of patients entering the study had gd+ lesions at baseline (mean number of gd+ lesions 1.4).

alghetkel oli 76% patsientidest raviresistentsed viimase raviliini suhtes, 64% olid raviresistentsed nii pi kui ka imid suhtes, 60% olid raviresistentsed alküülivate ainete suhtes, 36% olid raviresistentsed pomalidomiidi ja 17% karfilsomiibi suhtes.
at baseline, 76% of patients were refractory to the last line of treatment, 64% were refractory to both a pi and imid, 60% were refractory to alkylating agents, 36% were refractory to pomalidomide and 17% were refractory to carfilzomib.