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interferon beta-1b nedsætter bindingsaffiniteten og øger internaliseringen og nedbrydningen af inteferon-gamma receptorerne.
interferon beta-1b both decreases the binding affinity and enhances the internalisation and degradation of the interferon-gamma receptor.
Laatste Update: 2017-04-26
Gebruiksfrequentie: 3
Kwaliteit:
bindingsaffiniteten til den menneskelige endotelin- receptor er 65 gange mindre for 4- hydroxyetylambrisentan end for ambrisentan.
the binding affinity of 4-hydroxymethyl ambrisentan for the human endothelin receptor is 65-fold less than ambrisentan.
Laatste Update: 2012-04-12
Gebruiksfrequentie: 4
Kwaliteit:
bindingsaffiniteten til den menneskelige endotelin-receptor er 65 gange mindre for 4-hydroxyetyl-ambrisentan end for ambrisentan.
the binding affinity of 4-hydroxymethyl ambrisentan for the human endothelin receptor is 65-fold less than ambrisentan.
Laatste Update: 2017-04-26
Gebruiksfrequentie: 1
Kwaliteit:
det er usandsynligt, at ziconotids nedbrydningsprodukter vil have signifikant biologisk aktivitet, da peptider bestående af individuelle peptid løkke-strukturer har vist sig at have bindingsaffiniteter for n-type spændingsafhængige calciumkanaler, der er flere størrelsesordener lavere end moderstoffets (ziconotid).
it is unlikely that the degradation products of ziconotide will have significant biological activity, as peptides consisting of the individual peptide loop structures have been found to have binding affinities for n-type voltage sensitive calcium channels that are several orders of magnitude lower than that of the parent (ziconotide) compound.
Laatste Update: 2017-04-26
Gebruiksfrequentie: 5
Kwaliteit: