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fordelingsvolumenet er ikke dosisafhængigt.
the volume of distribution is not dose dependent.

fordelingsvolumenet er 0,3 1/kg.
the volume of distribution is 0.3 1/kg.

fordelingsvolumenet er 53-93 liter.
the volume of distribution is 53 - 93 litres.

fordelingsvolumenet er 2,6 l/kg.
the volume of distribution is 2.6 l/kg.

fordelingsvolumenet er 20- 40 l/ kg.
20 - 40 l/ kg).

fordelingsvolumenet er ca.1, 7 l/kg.
the volume of distribution is approximately 1.7 l/kg.

fordelingsvolumenet er moderat, idet vss er cirka 50 liter.
the volume of distribution is moderate with vss being approximately 50 litres.

fordelingsvolumenet er ved steady state cirka 10-14 l.
the steady state volume of distribution is around 10-14 l.

fordelingsvolumenet ved steady state efter intravenøs mikrodosisadministration er 46 l.
the steady-state volume of distribution following intravenous microdose administration is 46 l.

fordelingsvolumenet ved steady state efter intravenøs administration er cirka 5,41.
the volume of distribution at steady-state following intravenous administration is approximately 5.4 l.

den inter - individuelle variation i fordelingsvolumenet for parathyreoideahormon er omkring 40%.
intersubject variability in the volume of distribution of parathyroid hormone is about 40%.

fordelingsvolumenet kan ikke bestemmes på grund af den ringe absorption og mangel på defineret systemisk farmakokinetik.
the volume of distribution cannot be determined because the active substance is minimally absorbed and has no defined systemic pharmacokinetics.

fordeling fordelingsvolumenet kan ikke bestemmes på grund af den ringe absorption og mangel på defineret systemisk farmakokinetik.
distribution the volume of distribution cannot be determined because the drug is minimally absorbed and has no defined systemic pharmacokinetics.

efter intravenøs administration var fordelingsvolumenet 816 liter, hvilket antyder en udtalt fordeling til vævene hos mennesker.
after intravenous administration, the volume of distribution was 816 l, suggesting wide distribution to tissues in humans.

70% bundet til plasmaproteiner, og fordelingsvolumenet i steady- state er næsten 100 l hos patienter.
distribution ivabradine is approximately 70% plasma protein bound and the volume of distribution at steady-state is close to 100 l in patients.

fordeling efter intravenøs indgivelse blev steady-state fordelingsvolumenet af tenofovir vurderet til at være ca.800 ml/kg.
distribution following intravenous administration the steady-state volume of distribution of tenofovir was estimated to be approximately 800 ml/kg.

på basis af den farmakokinetiske populationsanalyse viste køn og vægt sig at have indflydelse på clearancen af oralt dabrafenib; vægten påvirkede også fordelingsvolumenet og den interkompartmentelle clearance.
based on the population pharmacokinetic analysis, gender and weight were found to influence dabrafenib oral clearance; weight also impacted oral volume of distribution and distributional clearance.

distribution ivabradin er ca.70% bundet til plasmaproteiner, og fordelingsvolumenet i steady-state er næsten 100 l hos patienter.
distribution ivabradine is approximately 70% plasma protein bound and the volume of distribution at steady-state is close to 100 l in patients.

efter at raske forsøgspersoner havde fået en intravenøs enkeltdosis på 12,5 mg alogliptin, var fordelingsvolumenet i den terminale fase 417 l, hvilket indikerer, at lægemidlet fordeles godt i vævene.
following a single intravenous dose of 12.5 mg alogliptin to healthy subjects, the volume of distribution during the terminal phase was 417 l indicating that the drug is well distributed into tissues.

efter intravenøs administration var fordelingsvolumenet af lomitapid højt (gennemsnit = 1200 l) trods høj plasmaproteinbinding (> 99.8 %).
following intravenous administration, the volume of distribution of lomitapide was high (mean=1200 litres) despite a high degree (>99.8%) of binding to plasma protein.