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(ilp)
(ilp)

farmakodynamiske forhold ved ilp
pharmacokinetics in ilp

kontraindikationer for ilp-proceduren:
contraindications to the ilp procedure:

kontraindikationer overfor ilp- proceduren:
contraindications to the ilp procedure:

beromun bør administreres via let hypertermisk ilp.
beromun should be administered by mild hyperthermic ilp.

5 patienter monitoreres i de første tre dage efter ilp.
therefore patients should be monitored during the first three days after the ilp.

derfor bør patienter monitoreres i de første tre dage efter ilp.
therefore patients should be monitored during the first three days after the ilp.

under ilp anbefales monitorering af centralt venøst tryk og arterielt tryk.
during the ilp, central venous pressure and arterial pressure monitoring is strongly recommended.

før påbegyndelse af ilp- procedure se da venligst produktresuméet for melfalan.
please refer to the spc of melphalan prior to commencing an ilp procedure.

bivirkningerne er enten lokale, påvirkede ekstremiteterne behandlet med ilp eller systemiske.
adverse reactions are either local, affecting the limb treated with ilp, or systemic.

om nødvendigt kan en yderligere ilp overvejes 6-8 uger efter den første ilp.
when necessary a second ilp can be considered 6-8 weeks after the first ilp.

i tilfælde af alvorligt shock inden afslutningen af ilp bør ekstremitetsperfusionen afbrydes og passende behandling påbegyndes.
in the event of severe shock before the end of the ilp, the limb perfusion should be discontinued and appropriate therapy administered.

beromun vil derfor blive indgivet af en læge som har viden og erfaring i ilp- teknikken.
beromun will therefore be administered to you by a doctor who is experienced and skilled in the technique of ilp.

efter ilp bør en standard udvaskningsprocedure altid anvendes, idet man skal anvende dextran 70 intravenøs infusionsvæske eller lignende væske.
following the ilp, a standard wash-out procedure should always be employed, using dextran 70 intravenous infusion or similar fluid.

pulver og solvens til infusionsvæske, opløsning (til brug ved isoleret ekstremitetsperfusion; ilp).
powder and solvent for solution for infusion (for isolated limb perfusion; ilp).

beromun vil blive givet af en læge, som har viden og erfaring i isoleret ekstremitetsperfusion (ilp).
beromun will be administered by a doctor who is experienced and skilled in isolated limb perfusion (ilp).

derudover bør monitorering af blodtryk, diurese samt elektrokardiografi foretages løbende de første 24-48 timer efter ilp, eller længere hvis indikeret.
furthermore, blood pressure, urine output and electrocardiographic monitoring should be routinely undertaken in the first 24 to 48 hours post-ilp, or longer if indicated.

et swan- ganz kateter bør overvejes til monitorering af pulmonalt arterielt tryk og ” wedge ” tryk under ilp samt postoperativt.
a swan-ganz catheter may be considered for monitoring pulmonary artery pressure and wedge pressure during the ilp and in the post-operative period.