Je was op zoek naar: moderstof (Deens - Engels)

moderstof
parent drug

cipac-nr. 358 (moderstof)
cipac no 358 (parent)

cas-nr.: 185119-76-0 (moderstof)
cas no 185119-76-0 (parent)

moderstof og smap kan yderligere blive glukoronideret.
parent drug and smap can additionally be glucuronidated.

40843-25-2 (moderstof) cas-nr.
cas no 40843-25-2 (parent)

kontrol af stabilitet ved hjælp af massebalance over moderstof
tier 2 if mass balance < 90%, test substance is unstable in the time scale of the test.

mindre end 0,1 % af den udskilte dosis blev genfundet som moderstof i urinen.
less than 0.1% of the excreted dose was recovered as parent in urine.

om total radioaktivitet eller moderstof og/eller metabolitter analyseres, afhænger af det undersøgte spørgsmål.
whether total radioactivity or parent chemical and/or metabolites are analysed will also depend on the issue being addressed.

rifabutin (moderstof og den aktive 25-o-desacetyl metabolit): auc: ↑ 5,7-gange
rifabutin (parent drug and active 25-o-desacetyl metabolite): auc: ↑ 5.7-fold

hovedmetabolitterne er sulfater og glucuronidkonjugater af moderstoffet samt n-desalkyl-metabolitter, som er biologisk inaktive.
main metabolites are sulfates and glucuronide conjugates of the parent compound as well as n-desalkyl-metabolites, which are biologically inactive.