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der sås ingen mutagene virkninger i en undersøgelse med bakteriel tilbagemutation (“ames test”) af det cysteaminbitartrat, der anvendes til procysbi.
a bacterial reverse mutation assay study (“ames test”) was performed with the cysteamine bitartrate used for procysbi and cysteamine bitartrate did not show any mutagenic effects in this test.
amprenavir var ikke mutagent eller genotoksisk i en række genetiske toxicitets assays foretaget in vivo og in vitro herunder bakterielle tilbagemutations (ames) test, muselymfomcelletest, mikronukleusundersøgelse hos rotter og kromosomafvigelsesprøve med perifere, humane lymfocytter.
amprenavir was not mutagenic or genotoxic in a battery of in vivo and in vitro genetic toxicity assays, including bacterial reverse mutation (ames test), mouse lymphoma, rat micronucleus, and chromosome aberration in human peripheral lymphocytes.
