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tolerabilitet og sikkerhed
tolerability and safety

patienter med ringe tolerabilitet
patients with poor tolerability

gastrointestinal tolerabilitet og sikkerhedsresultater:
gastrointestinal tolerability and safety results:

kronisk toksicitet og lokal tolerabilitet
repeated dose toxicity and local tolerance

helingsprocent og tolerabilitet afhang af lyskilden.
clearance rates and tolerability were dependent on the illumination source.

dosis kunne også nedsættes afhængigt af tolerabilitet.
doses could also be decreased depending on tolerability.

dosisregulering bør baseres på klinisk respons og tolerabilitet.
dose escalation should be based upon clinical response and tolerability.

denne infusionshastighed kan justeres, baseret på patientens tolerabilitet.
this infusion rate may be adjusted, based upon patient tolerability.

doseringen skal justeres individuelt, afhængigt af respons og tolerabilitet.
the posology is to be adjusted individually depending on response and tolerability.

enkeltdoser på op til 200 mg er givet med acceptabel akut tolerabilitet.
single doses up to 200 mg have been given with acceptable acute tolerability.

en langsom stigning i dosis kan også forbedre den gastrointestinale tolerabilitet.
a slow increase in the dose may also improve gastrointestinal tolerability.

dosis kan øges til 80 mg dagligt i henhold til respons og tolerabilitet.
the dose may be increased to 80 mg daily, according to the response and tolerability.

protopys tolerabilitet ved behandling af patienter med generaliseret erythrodermi er ikke undersøgt.
the safety of protopy ointment has not been established in patients with generalised erythroderma.

anbefalinger vedr. dosistitrering skal følges nøje i henhold den enkelte patients tolerabilitet.
dosing recommendations to titrate according to individual tolerability must be closely followed.

eftersom tolcapon ikke ændrede ephedrins tolerabilitet, kan de to lægemidler anvendes sammen.
since tolcapone did not alter the tolerability of ephedrine, these drugs can be co-administered.

afhængigt af patientens respons og tolerabilitet kan dosis efter 7 dage øges til 300 mg dagligt.
based on individual patient response and tolerability, the dosage may be increased to 300 mg per day after 1 week.

eventuel efterfølgende dosisjustering skal følge den kliniske effekt (tolerabilitet og virkning).
it is therefore advised that paroxetine should be gradually tapered when discontinuing treatment over a period of several weeks or months, according to the patient’ s needs (see "withdrawal symptoms seen on discontinuation of paroxetine", section 4.2 posology and method of administration).

dosis pr. inhalationsbehandling bør administreres 6 til 9 gange dagligt efter patientens behov og tolerabilitet.
the dose per inhalation session should be administered 6 to 9 times per day according to the individual need and tolerability.

studiet undersøgte farmakokinetik, sikkerhed og tolerabilitet, såvel som virologiske og immunologiske respons gennem 48 uger.
the trial evaluated pharmacokinetics, safety and tolerability, as well as virologic and immunologic responses through 48 weeks.

derefter kan forsigtig titrering overvejes, afhængigt af ldl-c-respons og sikkerhed/tolerabilitet.
careful titration may then be considered according to ldl-c response and safety/tolerability.