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composite endpoint
punt ta’ tmiem kompost

composite endpoint §
immunoġeniċità

primary composite endpoint
endpoint kompost primarju

primary composite endpoint at week 32
endpoint kompost primarju fit-32 Ġimgħa

composite nps ae primary endpoint, n (%)
punt tat-tmiem primarju tal-ae nps kompost, n (%)

composite endpoint a6 species (hpv 56) †
speċi a6 (hpv 56) †

individual components of the primary composite endpoint
komponenti individwali tal-endpoint kompost primarju

secondary composite endpoints
punti ewlenin sekondarji komposti

primary composite endpoint of cv death and heart failure hospitalisations*
endpoint kompost primarju ta’ mewt cv u ospitalizzazzjonijiet ta’ pazjenti b’insuffiċjenza tal- qalb

response assessment was based on a composite endpoint defined as above.
valutazzjoni tar-rispons kienet ibbażata fuq punt finali (endpoint) kompost definit kif imsemmi hawn fuq.

treatment effect on the primary composite endpoint, its components and secondary endpoints
effett tal-kura fuq l-endpoint kompost primarju, il-komponenti tiegħu u l-endpoints sekondarji

the presap trial did not demonstrate a statistically significant increased risk for the same composite endpoint.
il-prova presap ma wrietx żieda statistika sinifikanti fir- riskju għall-istess endpoint kompost.

figure 1 kaplan-meier curves for the primary composite endpoint and the cv death component
figura 1 kurvi kaplan-meier għall-endpoint kompost primarju u għall-komponent ta’ mewt cv

secondary composite endpoint (cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke)
skop finali kompost sekondarju (mewt kardjovaskulari, infart mijokardijaku mhux fatali, jew puplesija mhux fatali)

relative to placebo, xarelto significantly reduced the primary composite endpoint of cv death, mi or stroke.
mqabbel mal-plaċebo, xarelto naqqas b’mod sinifikanti l-punt finali primarju kompost ta’ mewt cv, mi jew puplesija.

the key secondary composite endpoint (adpkd progression) was time to multiple clinical progression events of:
il-punt finali sekondarju kompost kruċjali (key secondary composite endpoint) (progressjoni ta’ adpkd) kien iż-żmien sakemm seħħew avvenimenti multipli ta’ progressjoni klinika ta’:

figure 1 – analysis of primary clinical composite endpoint of cv death, mi and stroke (plato)
figura 1 – analiżi tal-punt ta’ tmiem kompost primarju ta’ mewt cv, mi u puplesija (plato)

figure 2 - analysis of primary clinical composite endpoint of cv death, mi and stroke (pegasus)‌
figura 2 – analiżi tal-punt ta’ tmiem kompost kliniku primarju ta’ mewt cv, mi u puplesija (pegasus)

the result of the key secondary composite endpoint is primarily attributed to effects on worsening kidney function and medically significant kidney pain.
ir-riżultat tal-punt finali sekondarju kompost kruċjali (key secondary composite endpoint) huwa primarjament attribwit għall-effetti fuq funzjoni tal-kliewi li qed taggrava u fuq uġigħ fil-kliewi li huwa medikament sinifikanti.

patients treated with rilonacept experienced more improvement in each of the five components of the composite endpoint than placebo-treated patients.
pazjenti kkurati b’rilonacept kellhom iktar titjib f’kull wieħed mill-ħames komponenti tal-punt aħħari kompost milli mill-pazjenti kkurati bil-plaċebo.