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patients were also required to have documented confirmation of the presence of a nonsense mutation in the dystrophin gene as determined by gene sequencing.
prav tako so bolniki morali imeti potrdilo o prisotnosti nesmiselne mutacije gena za distrofin, ki je bila ugotovljena s sekvenciranjem genov.
iressa works only in non-small cell lung cancer cells that have a mutation in their egfr.
zdravilo iressa deluje samo na celice nedrobnoceličnega pljučnega raka, ki imajo mutacijo receptorja za epidermalni rastni dejavnik.
the results of the study were analysed separately in 243 patients whose tumours contained kras that had not mutated and in 184 patients in whom the kras gene contained a mutation.
rezultate te študije so analizirali ločeno pri 243 bolnikih, pri katerih so tumorji vsebovali gen kras, ki ni mutiral, in pri 184 bolnikih, pri katerih je gen kras vseboval mutacijo.
some types of mast-cell tumour are linked to a mutation that causes excessive action of c-kit and stimulates the mast cells to divide uncontrollably.
nekatere vrste mastocitomov so povezane z mutacijo, ki povzroča čezmerno delovanje beljakovine c-kit in spodbuja mastocite k nenadzorovanemu razmnoževanju.
those control measures aim at preventing the spread of lpai of h5 and h7 subtypes before they become widespread in the domestic poultry population so that the risk of a mutation into hpai with possibly devastating consequences may be prevented.
namen navedenih ukrepov nadzora je preprečevanje širjenja lpai podtipov h5 in h7, preden se razširita v populaciji domače perutnine, s čimer se prepreči tveganje mutacije v hpai z možnimi hudimi posledicami.
patients must have confirmation of a breast cancer susceptibility gene (brca) mutation (either germline or tumour) before lynparza treatment is initiated.
pred uvedbo zdravljenja z zdravilom lynparza morajo imeti bolnice potrjeno mutacijo gena brca (gen dovzetnosti za raka dojk), bodisi germinalno bodisi v tumorju.
it is said that the ribera del xúquer region is the cradle of the ‘rojo brillante’ persimmon, as that is where this variety emerged as a result of a spontaneous mutation.
za regijo ribera del xúquer velja, da je zibelka kakija „rouge brillant“, saj se je ta sorta pojavila v tej regiji po samodejni mutaciji;
the presence of k103n alone, which was the most prevalent nnrti mutation in duet-1 and duet-2 at baseline, was not identified as a mutation associated with resistance to intelence.
prisotnost samo k103n ni bila opredeljena kot mutacija, povezana z odpornostjo na zdravilo intelence.
and bridges, b. a. (1976), use of a simplified fluctuation test to detect low levels of mutagens, mutation res., 38, pp. 33-42.
j., in bridges, b. a. (1976), use of a simplified fluctuation test to detect low levels of mutagens, mutation res., 38, str. 33-42.
those surveillance programmes aim at identifying the circulation of lpai viruses in poultry, in particular in waterfowl poultry species, before they become widespread in the poultry population, so that control measures can be taken to possibly prevent a mutation into a hpai virus which might have devastating consequences.
cilj navedenih programov nadzora je opredelitev kroženja virusov lpai pri perutnini, zlasti pri vodnih vrstah perutnine, preden se razširijo med populacijo perutnine, tako da se lahko sprejmejo nadzorni ukrepi za morebitno preprečitev mutacije v virus hpai, kar bi lahko imelo hude posledice.