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ipilimumaab
ipilimumab

yervoy ipilimumaab
yervoy ipilimumab

yervoy toimeaine ipilimumaab on monoklonaalne antikeha.
the active substance in yervoy, ipilimumab, is a monoclonal antibody.

ctla-4 blokeerides võimaldab ipilimumaab aktiveeruda ja levida t-rakkudel, mis infiltreeruvad ja tapavad kasvajarakud
ipilimumab, by blocking ctla-4, leads to the activation and spread of the t cells, which infiltrate tumours and kill the tumour cells.

ipilimumaab seondub teatud valgeliblede, t-rakkude pinnal leiduva valgu ctla-4-ga ning blokeerib selle toime.
ipilimumab has been designed to attach to and block the activity of a protein called ctla-4 that is found on the surface of t cells, a type of white blood cell.