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Indonesisch

apa ini masih ada

Engels

这个还有吗

Laatste Update: 2022-02-19
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

selama persediaan masih ada

Engels

applies multiply

Laatste Update: 2019-04-18
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

masih ada yang ditutupi dari saya

Engels

the most potent suppressors of gastric acid secretion are inhibitors of the gastric h+,k+-atpase (proton pump) (figure 36–2a). in typical doses, these drugs diminish the daily production of acid (basal and stimulated) by 80% to 95%. five proton pump inhibitors are available for clinical use: omeprazole (prilosec, rapinex, zegerid) and its s-isomer, esomeprazole (nexium), lansoprazole (prevacid), rabeprazole (aciphex), and pantoprazole (protonix). these drugs have different substitutions on their pyridine and/or benzimidazole groups but are remarkably similar in their pharmacological properties (see appendix ii). omeprazole is a racemic mixture of r- and s-isomers; the s-isomer, esomeprazole (s-omeprazole), is eliminated less rapidly than r-omeprazole, which theoretically provides a therapeutic advantage because of the increased half-life. despite claims to the contrary, all proton pump inhibitors have equivalent efficacy at comparable doses. proton pump inhibitors are prodrugs that require activation in an acid environment. after absorption into the systemic circulation, the prodrug diffuses into the parietal cells of the stomach and accumulates in the acidic secretory canaliculi. here, it is activated by proton-catalyzed formation of a tetracyclic sulfenamide (figure 36–2), trapping the drug so that it cannot diffuse back across the canalicular membrane. the activated form then binds covalently with sulfhydryl groups of cysteines in the h+,k+-atpase, irreversibly inactivating the pump molecule. acid secretion resumes only after new pump molecules are synthesized and inserted into the luminal membrane, providing a prolonged (up to 24- to 48-hour) suppression of acid secretion, despite the much shorter plasma half-lives (0.5 to 2 hours) of the parent compounds. because they block the final step in acid production, the proton pump inhibitors are effective in acid suppression regardless of other stimulating factors. the most potent suppressors of gastric acid secretion are inhibitors of the gastric h+,k+-atpase (proton pump) (figure 36–2a). in typical doses, these drugs diminish the daily production of acid (basal and stimulated) by 80% to 95%. five proton pump inhibitors are available for clinical use: omeprazole (prilosec, rapinex, zegerid) and its s-isomer, esomeprazole (nexium), lansoprazole (prevacid), rabeprazole (aciphex), and pantoprazole (protonix). these drugs have different substitutions on their pyridine and/or benzimidazole groups but are remarkably similar in their pharmacological properties (see appendix ii). omeprazole is a racemic mixture of r- and s-isomers; the s-isomer, esomeprazole (s-omeprazole), is eliminated less rapidly than r-omeprazole, which theoretically provides a therapeutic advantage because of the increased half-life. despite claims to the contrary, all proton pump inhibitors have equivalent efficacy at comparable doses. proton pump inhibitors are prodrugs that require activation in an acid environment. after absorption into the systemic circulation, the prodrug diffuses into the parietal cells of the stomach and accumulates in the acidic secretory canaliculi. here, it is activated by proton-catalyzed formation of a tetracyclic sulfenamide (figure 36–2), trapping the drug so that it cannot diffuse back across the canalicular membrane. the activated form then binds covalently with sulfhydryl groups of cysteines in the h+,k+-atpase, irreversibly inactivating the pump molecule. acid secretion resumes only after new pump molecules are synthesized and inserted into the luminal membrane, providing a prolonged (up to 24- to 48-hour) suppression of acid secretion, despite the much shorter plasma half-lives (0.5 to 2 hours) of the parent compounds. because they block the final step in acid production, the proton pump inhibitors are effective in acid suppression regardless of other stimulating factors.

Laatste Update: 2014-04-24
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

berlaku selama persediaan masih ada

Engels

while supplies last

Laatste Update: 2019-04-12
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

dia menjawab: "masih ada tambahan?"

Engels

it will say, "are there any more (to come)?"

Laatste Update: 2014-07-03
Gebruiksfrequentie: 2
Kwaliteit:

Referentie: Anoniem
Waarschuwing: Bevat onzichtbare HTML-opmaak

Indonesisch

masih ada syarat yang harus dilengkapi

Engels

there are still obstacles

Laatste Update: 2012-04-22
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

masih berada di episode menunggu

Engels

masih berada di episode menunggu

Laatste Update: 2024-01-26
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

biarlah kita merendahkan diri dan menyerah, karena mungkin harapan masih ada

Engels

he putteth his mouth in the dust; if so be there may be hope.

Laatste Update: 2012-05-06
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

dengarkanlah sebentar lagi, dan bersabarlah, masih ada yang hendak kukatakan demi allah

Engels

elihu also proceeded, and said,

Laatste Update: 2012-05-06
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

wabah virus covid 19 masih ada saat ini, covid 19 awalnya berasal dari china

Engels

the covid 19 virus outbreak still exists today, covid 19 originally came from china

Laatste Update: 2022-03-23
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

sudah tamat kuliah kenapa masih ada bimbingan sama dosen lagi agar bisa diperbolehkan jilid skripsi ??

Engels

already graduated from college why there is still the same guidance teacher again?

Laatste Update: 2010-10-28
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

pertandingan lain yang dijadwalkan hari rabu masih diadakan, menurut kantor berita nbc.

Engels

other games scheduled for wednesday were still held, according to nbc news.

Laatste Update: 2020-08-25
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

daerah crystal creek, sis barat black range semakin parah - mengungsi sekarang, selama masih ada kesempatan

Engels

strictly, a writer and web publisher living in brisbane, provided a lot of information.

Laatste Update: 2016-02-24
Gebruiksfrequentie: 1
Kwaliteit:

Referentie: Anoniem

Indonesisch

lalu jahanam menjawab dengan marah kepada mereka, "masih adakah tambahan yang lain dari orang-orang yang zalim itu?"

Engels

it will say, "are there any more (to come)?"

Laatste Update: 2014-07-03
Gebruiksfrequentie: 2
Kwaliteit:

Referentie: Anoniem
Waarschuwing: Bevat onzichtbare HTML-opmaak

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