Je was op zoek naar: deseterostruko (Kroatisch - Engels)

deseterostruko povećati sigurnost,
improve safety by a factor of 10;

bubrežni klirens tih neaktivnih metabolita bio je deseterostruko smanjen.
the renal clearance of these non active metabolites was decreased 10-fold.

mačke podnose do deseterostruko veću dozu od preporučene bez dokaza nepovoljnih učinaka ili nepoželjnih kliničkih simptoma.
up to 10 times the recommended dose was tolerated in cats with no evidence of adverse effects or undesirable clinical signs.

s vladinim podatcima koji pokazuju deseterostruko povećanje od 2004. godine, premijer sali berisha težio je učiniti taj sektor glavnim prioritetom.
with government data showing a tenfold increase since 2004, prime minister sali berisha has sought to make the sector a top priority.

kako bi riješila taj problem, tvornica za proizvodnju i konzerviranje ribe, ribarstvo, planira seriju projekata čiji je cilj deseterostruko povećanje kapaciteta.
to address this problem, the ribarstvo fish production and canning factory plans a series of projects designed to increase capacity ten fold.

u otprilike pola slučajeva naglog porasta koji je deseterostruko premašivao gornju granicu normale, doza lijeka pegasys je smanjena ili izostavljena sve do normalizacije razina transaminaza, dok je u drugoj polovici terapija nastavljena bez promjena.
in approximately half the cases of flares exceeding 10 times the upper limit of normal, pegasys dosing was reduced or withheld until the transaminase elevations subsided, while in the rest therapy was continued unchanged.

budući da je podnošljivost deseterostruko veće doze (3 mg po oku) bila dobra, očekuje se da će sistemska izloženost biti unutar raspona koji bolesnici s oštećenjem jetrene funkcije mogu lako podnijeti.
the systemic exposure is expected to be within a well tolerated range in patients with hepatic impairment, as a 10 fold higher dose (3 mg/eye) was well tolerated.

in vivo je u ljudskih ispitanika s neutralnim mutacijama enzima cyp2c19 stvaranje hidroksi metabolita deseterostruko smanjeno, dok je koncentracija brivaracetama povećana za 22% odnosno 42% u osoba s jednim odnosno oba mutirana alela.
in vivo, in human subjects possessing ineffective mutations of cyp2c19, production of the hydroxy metabolite is decreased 10- fold while brivaracetam itself is increased by 22 % or 42 % in individuals with one or both mutated alleles.

obje prirođene bolesti iznimno su rijetke s prevalencijom u europi od otprilike 3 do 5 bolesnika s deficijencijom 3β-hidroksiΔ5-c27-steroid oksidoreduktaze na 10 milijuna stanovnika i procijenjenom deseterostruko manjom prevalencijom deficijencije Δ4-3-oksosteroid-5β-reduktaze.
both inborn dieseases are extremely rare, with a prevalence in europe of about 3 to 5 patients with 3β-hydroxy-Δ5-c27-steroid oxidoreductase deficiency per 10 million inhabitants, and an estimated ten-fold lower prevalence for Δ4-3-oxosteroid-5β-reductase deficiency.