Je was op zoek naar: parahidroksisulfato (Lithouws - Engels)

pagrindinio metabolito (parahidroksisulfato) sujungimo laipsnis su baltymais yra labai didelis ( 99, 99) .
the protein binding of the major metabolite (a para-hydroxy-sulphate) is very high ( 99.99%) .

pagrindinio metabolito (parahidroksisulfato) sujungimo laipsnis su baltymais yra labai didelis (> 99,99 ).
the protein binding of the major metabolite (a para-hydroxy-sulphate) is very high (> 99.99%).

kartotini dozi metu laukiama metabolit kumuliacija plazmoje, ypac pagrindinio metabolito (parahidroksisulfato) , ir galima tiktis 8 kartus didesnio jo susikaupimo.
accumulation of the metabolites in plasma is expected upon repeated dosing, especially that of the major metabolite (a para-hydroxy-sulphate) for which an 8-fold accumulation is anticipated.

pagrindinio metabolito (parahidroksisulfato) reiksm bendram antihiperglikeminiam poveikiui zmonms nra visiskai isaiskinta, todl neatmetama galimyb, kad metabolitai gali nesti savo aktyvumo dal.
the contribution of the major metabolite (a para-hydroxy-sulphate) to the overall antihyperglycaemic activity of rosiglitazone has not been fully elucidated in man and it cannot be ruled out that the metabolite may contribute to the activity.

pagrindinio metabolito (parahidroksisulfato) reikšmė bendram antihiperglikeminiam poveikiui žmonėms nėra visiškai išaiškinta, todėl neatmetama galimybė, kad metabolitai gali įnešti savo aktyvumo dalį.
the overall antihyperglycaemic activity of rosiglitazone has not been fully elucidated in man and it cannot be ruled out that the metabolite may contribute to the activity.

pagrindinis metabolitas (parahidroksisulfatas) , kuriam bdingas didelis afinitetas tirpiems zmogaus ppar, pasizymjo stipriu veikimu gliukozs tolerancijos bandymuose su nutukusiomis pelmis.
the major metabolite (a para-hydroxy-sulphate) with high affinity to the soluble human ppar, exhibited relatively high potency in a glucose tolerance assay in obese mice.