Je was op zoek naar: mdr (Maltees - Engels)

macitentan mhuwiex sottostrat għal p-gp/mdr-1.
macitentan is not a substrate for p- gp/mdr-1.

trasportaturi mdr oħra jista’ jkollhom ukoll rwol fit-trasport ta’ dexamethasone.
other mdr transporters may also have a role in dexamethasone transport.

barra minn hekk, tagħrif kliniku ristrett jindika li ż-żieda ta’ delamanid ma’ programmi ta’ kura għall-kura ta’ mdr-tb li kienu reżistenti għal ripampicin u isoniazid imma pjuttost suxxettibbli, ipprovdew l-ogħla effikaċja filwaqt li l-użu ta’ delamanid bħala parti mill-aħjar programmi ta’ kura disponibbli għat-trattament ta’ xdr-tb kien assoċjati mal-inqas effikaċja.
in addition, limited clinical data indicate that the addition of delamanid to regimens for treating mdr-tb that were resistant to rifampicin and isoniazid but otherwise susceptible, gave the highest efficacy whereas use of delamanid as part of the best available regimens that could be constructed for treating xdr-tb was associated with the lowest efficacy.