Je was op zoek naar: somatostatina (Maltees - Engels)

bħas- somatostatina, il-pasireotide teħel ma’ dawn ir-riċetturi.
like somatostatin, pasireotide attaches to these receptors.

għotja sperimentali tal - prodott medicinali wasslet għal nuqqas ta 'somatostatina f’ diversi speċi ta ’ annimali.
experimental administration of the drug causes depletion of somatostatin in several animal species.

għalkemm il-kumitat ikkunsidra li dan ir- riskju jista’ jiġi mmonitorjat u ġestit faċilment b’mediċini standard tad-dijabete, is-chmp ikkunsidra li analogi oħrajn ta’ somatostatina għandhom jiġu ppruvati l-ewwel f’pazjenti b’akromegalija u l-użu ta’ signifor għandu jinżamm għal dawk li l-kundizzjoni tagħhom ma kinitx ikkontrollata b’dawn il-mediċini alternattivi.
although the committee considered that this risk could be easily monitored and managed with standard diabetes medicines, the chmp considered that other somatostatin analogues should be tried first in patients with acromegaly and use of signifor should be reserved for those whose condition was not controlled by these alternative medicines.