Je was op zoek naar: adenokarcinome (Sloveens - Engels)

v drugi študiji je subkutano injiciranje cidofovira 19 tednov zapored pri podganjih samicah povzročilo mamarne adenokarcinome že v odmerkih 0,6 mg/kg/teden.
in a separate study, once weekly subcutaneous injections of cidofovir for 19 consecutive weeks resulted in mammary adenocarcinomas in female rats at doses as low as 0.6 mg/kg/week.

značilnosti bolezni so bile naslednje: 91 % metastatski primeri, 96 % histološko razvrščenih med adenokarcinome in 13 % brez predhodnega sistemskega zdravljenja metastatske bolezni.
the disease characteristics were 91% metastatic, 96% adenocarcinoma histology, and 13% with no prior systemic therapy for metastatic disease.

adenome/karcinome ledvic, papilome sečnega mehurja in sečnice, adenokarcinome tankega črevesa, adenome obščitničnih žlez, benigne in maligne medularne tumorje nadlevičnih žlez in papilome/karcinome ne-žleznega dela želodca so opazili pri odmerku 60 mg/kg/dan, kar predstavlja približno 1,7 do 1-kratnik dnevne izpostavljenosti človeka (na podlagi auc) pri odmerku 400 mg/dan oziroma 800 mg/dan in 1,2-kratnik dnevne izpostavljenosti otrok (na podlagi auc) pri 340 mg/m2/dan.
the renal adenoma/carcinoma, the urinary bladder and urethra papilloma, the small intestine adenocarcinomas, the parathyroid glands adenomas, the benign and malignant medullary tumours of the adrenal glands and the non-glandular stomach papillomas/carcinomas were noted at 60 mg/kg/day, representing approximately 1.7 or 1 times the human daily exposure (based on auc) at 400 mg/day or 800 mg/day, respectively, and 1.2 times the daily exposure in children (based on auc) at 340 mg/m2/day.