Je was op zoek naar: dehidroaripiprazol (Sloveens - Engels)

poleg tega aripiprazol in dehidroaripiprazol in vitro nista pokazala potenciala za spreminjanje presnove s cyp1a2.
additionally, aripiprazole and dehydro- aripiprazole did not show potential for altering cyp1a2-mediated metabolism in vitro.

v stanju dinamičnega ravnovesja predstavlja aktivni presnovek dehidroaripiprazol okrog 40 % auc aripiprazola v plazmi.
at steady state, dehydro-aripiprazole, the active metabolite, represents about 40 % of aripiprazole auc in plasma.

v terapevtskih koncentracijah sta aripiprazol in dehidroaripiprazol več kot 99 % vezana na beljakovine v serumu, predvsem na albumin.
at therapeutic concentrations, aripiprazole and dehydro-aripiprazole are greater than 99 % bound to serum proteins, binding primarily to albumin.

po večkratnem odmerjanju zdravila abilify maintena aktivni presnovek dehidroaripiprazol v stanju dinamičnega ravnovesja predstavlja približno 29,1-32,5 % auc aripiprazola v plazmi.
after multiple dose administration of abilify maintena, dehydro-aripiprazole, the active metabolite, represents about 29.1-32.5 % of aripiprazole auc in plasma.