Je was op zoek naar: makrociklični (Sloveens - Engels)

farmakoterapevtska skupina: antiparazitiki, insekticidi in repelenti, makrociklični laktoni.
pharmacotherapeutic group: antiparasitic products, insecticides and repellents, macrocyclic lactones.

farmakoterapevtska skupina: antiparazitiki, insekticidi in repelenti, makrociklični laktoni, milbemicini.
pharmacotherapeutic group: antiparasitic products, insecticides and repellents, macrocyclic lactones, milbemycins.

moksidektin 23-(0-methyloxime)-f28249 alfa je makrociklični lakton druge generacije in spada v skupino milbemicinov.
moxidectin, 23-(o-methyloxime)-f28249 alpha is a second-generation macrocyclic lactone of the milbemycin family.

moksidektin 23-(o-methyloxime)-f28249 alfa je makrociklični lakton druge generacije in spada v skupino milbemicinov.
moxidectin, 23-(o-methyloxime)-f28249 alpha is a second-generation macrocyclic lactone of the milbemycin family.

metaboliti, ki so jih odkrili v blatu, so nastali z oksidacijo na makrociklični ali aromatski skupini ali na obeh in z o-demetilacijo, ki ji sledi oksidacija.
metabolites identified in faeces were formed via oxidation at the macrocyclic moiety or aromatic moiety or both and by o-demethylation followed by oxidation.

milbemicin oksim je sistemski makrociklični lakton, ki vsebuje dva glavna dejavnika, a3 in a4 (razmerje a3 : a4 je 20 : 80).
milbemycin oxime is a systemic macrocyclic lactone containing two major factors, a3 and a4 (ratio of a3:a4 is 20:80).

sočasno zdravljenje s pripravki, ki so substrati/inhibitorji p- glikoproteinov (npr. ivermektin in drugi protiparazitarni makrociklični laktoni, eritromicin, prednizolon in ciklosporin), lahko povzroči farmakokinetične interakcije.
co-treatment with other drugs that are p-glycoprotein substrates/inhibitors (for example, ivermectin and other antiparasitic macrocyclic lactones, erythromycin, prednisolone and cyclosporine) could give rise to pharmacokinetic drug interactions.