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1-carboxy-1-methylethoxyammoniumchloride
1-carboxy-1-methylethoxyammonium chloride
Última atualização: 2014-11-21
Frequência de uso: 3
Qualidade:
carboxy-dabrafenib kan worden gedecarboxyleerd via een niet-enzymatisch proces om desmethyl-dabrafenib te vormen.
carboxy-dabrafenib can be decarboxylated via a non-enzymatic process to form desmethyl-dabrafenib.
circulerende carboxy- uiteindefragmenten worden gefilterd door de nieren maar worden vervolgens tijdens de tubulaire re- uptake afgebroken tot nog kleinere fragmenten.
circulating carboxy-terminal fragments are filtered by the kidney, but are subsequently broken to even smaller fragments during tubular reuptake.
de belangrijkste metabolieten die in alle species werden aangetroffen zijn de 5-hydroxy en 5-carboxy-metabolieten en de oxalyl-metaboliet.
the major metabolites found in all species were the 5-hydroxy- and 5-carboxy- metabolites and the oxalyl-metabolite.