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lymphopenia, deranged liver function tests, and elevated creatine kinase are common laboratory abnormalities of sars.
تُعد قلة اللمفاويات، واختلال وظائف الكبد، وارتفاع كيناز الكرياتين من الاختلالات المخبرية الشائعة لسارس.
the world health organization (who) has proclaimed coronavirus disease 2019 (covid-19) as a pandemic and a major public health emergency [1]. the illness ranges from asymptomatic or mild infection to acute respiratory distress syndrome (ards) with high mortality [1, 2]. presentations include fever, coughing, dyspnea, watery diarrhea, myalgia, severe lymphopenia, prolonged coagulation profiles, cardiac disease and sudden death [2, 3]. coagulopathy was frequently reported in covid-19 patients, especially among those with severe disease [4, 5]. d-dimer > 1 μg/ml is one of the risk factors of mortality in patients with covid-19 [4]. administration of low molecular weight heparin among patients with markedly elevated d-dimer level is significantly associated with better 28-day survival [6]. many autopsies of covid-19 patients showed thrombosis in small pulmonary vessels [7]. some retrospective studies found a high incidence of pe in covid-19 patients [8, 9] acute pe interferes with both circulation and gas exchange. right ventricular (rv) failure due to acute pressure overload is considered the primary cause of death in severe pe [10, 11]. d‐dimer is an indirect marker of fibrinolysis and fibrin turnover [12]. d‐dimer is a soluble fibrin degradation product that results from degradation of vascular thrombi through the fibrinolytic mechanism [12]. d‐dimer is used as a marker of activation of coagulation and fibrinolysis in a number of clinical scenarios. d-dimer test is used for exclusion of the diagnosis of venous thromboembolism (vte) and is used routinely for this indication [12].
الارتباط بين مستوى d dimer وتطور الانسداد الرئوي في المرضى الذين يعانون من فيروس كورونا الرئوي 19
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