You searched for: norgestrelio (Litauiska - Engelska)

norgestrelio
contraindicated

geriantiems sirolimuz ir kontraceptik, kurio sudtyje yra 0, 3 mg norgestrelio ir 0, 03 mg etinilestradiolio, klinikai reiksmingos farmakokinetins sveikos nepasireisk.
no clinically significant pharmacokinetic interaction was observed between rapamune oral solution and 0.3 mg norgestrel/0.03 mg ethinyl estradiol.

daug (> 97 %) norelgestromino ir norgestrelio (norelgestromino metabolitas kraujo serume) jungiasi su kraujo serumo baltymais.
norelgestromin and norgestrel (a serum metabolite of norelgestromin) are highly bound (> 97%) to serum proteins.

norelgestrominas jungiasi su albuminais, bet ne su lytinius hormonus prijungianciais globulinais (lhpg) , o norgestrelio daugiausiai prisijungia prie lhpg, tai riboja jo biologin aktyvum.
norelgestromin is bound to albumin and not to shbg, while norgestrel is bound primarily to shbg, which limits its biological activity.

norelgestrominas metabolizuojamas kepenyse.jo metabolitai yra norgestrelis, kurio didzioji dalis yra prisijungusi prie lhpg, ir vairs hidroksilinti ir konjuguoti metabolitai.
hepatic metabolism of norelgestromin occurs and metabolites include norgestrel, which is largely bound to shbg, and various hydroxylated and conjugated metabolites.