Şunu aradınız:: glucuronidated (İngilizce - Danca)

parent drug and smap can additionally be glucuronidated.
moderstof og smap kan yderligere blive glukoronideret.

there is no impact on glucuronidated-zdv levels.
35%. der er ingen påvirkning af glukuroniderede zdv - niveauer.

metabolites are then excreted in the bile as either free or glucuronidated metabolites.
metabolitterne udskilles herefter i galden, enten som frie eller som glucuroniderede metabolitter.

deferasirox is mainly glucuronidated by ugt1a1 and to a lesser extent ugt1a3.
deferasirox bliver primært gluconideret af ugt1a1 og i mindre grad af ugt1a3.

zidovudine is primarily eliminated by hepatic conjugation to an inactive glucuronidated metabolite.
zidovudin elimineres primært ved hepatisk konjugering til en inaktiv glucuronideret metabolit.

elvitegravir undergoes primarily oxidative metabolism via cyp3a, and is secondarily glucuronidated via ugt1a1/3 enzymes.
elvitegravir gennemgår primært oxidativ metabolisme via cyp3a og glukuronideres i mindre grad via ugt1a1/3-enzymer.

dextromethorphan is rapidly metabolized by cyp2d6 to its primary metabolite, dextrorphan, which is rapidly glucuronidated and renally eliminated.
dextromethorphan metaboliseres hurtigt af cyp2d6 til den primære metabolit dextrorphan, der hurtigt glukuronideres og udskilles renalt.

thus cytochrome p450 metabolism, glucuronide conjugation, and urinary excretion of glucuronidated metabolites represent the primary route of nevirapine biotransformation and elimination in humans.
cytokrom p450- metabolismen, glucuronide konjugater og den urinære ekskretion af glucuronide metabolitter repræsenterer således den primære rute for nevirapins biotransformation og elimination hos mennesket.

ambrisentan is glucuronidated via several ugt isoenzymes (ugt1a9s, ugt2b7s and ugt1a3s) to form ambrisentan glucuronide (13%).
ambrisentan bliver glukuronideret via adskillige ugt-isoenzymer (ugt1a9s, ugt2b7s og ugt1a3s), og derved dannes ambrisentan-glukuronid (13 %).

o-glucuronidation is the major metabolic elimination pathway for canagliflozin, which is mainly glucuronidated by ugt1a9 and ugt2b4 to two inactive o-glucuronide metabolites.
canagliflozin udskilles hovedsageligt via o-glucuronidering, og det glucuronideres især af ugt1a9 og ugt2b4 til to inaktive o-glucuronid-metabolitter.

in both species difloxacin may be conjugated (glucuronidated or sulphated), desmethylated into sarafloxacin or oxidised into n-oxide-difloxacin.
hos begge arter kan difloxacin konjugeres (glucuronideres eller sulfateres), demetyleres til sarafloxacin eller oxideres til n-oxid-difloxacin.

following oral administration of a 100 mg dose of a solution formulation of sorafenib, 96% of the dose was recovered within 14 days, with 77% of the dose excreted in faeces, and 19% of the dose excreted in urine as glucuronidated metabolites.
efter oral administration af en 100 mg dosis af en sorafenibopløsning blev 96% af dosis genfundet i løbet af 14 dage.heraf blev 77% af dosis udskilt via fæces, og 19% af dosis blev udskilt via urinen som glucuroniderede metabolitter.