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berekende regressiemodellering van de predictieve waarde van genotype (aangepast voor baseline plasma hiv-1rna [vrna], cd4+ cellenaantal, hoeveelheid en duur van voorgaande antiretrovirale therapieën) liet zien dat de aanwezigheid van 3 of meer nrti resistentie-geassocieerde mutaties samenging met een verminderde respons in week 4 (p=0,015) of 4 of meer mutaties in mediaan week 24 (p≤0,012).
logistic regression modelling of the predictive value for genotype (adjusted for baseline plasma hiv-1rna [vrna], cd4+ cell count, number and duration of prior antiretroviral therapies) showed that the presence of 3 or more nrti resistance-associated mutations was associated with reduced response at week 4 (p=0.015) or 4 or more mutations at median week 24 (p≤ 0.012).
Son Güncelleme: 2012-04-11
Kullanım Sıklığı: 8
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