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een studie bij ratten toonde ook passage van stavudine door de placenta, met een foetale weefselconcentratie van ongeveer 50% van die van de concentratie in het bloed van de moeder.
a rat study also showed placental transfer of stavudine, with the foetal tissue concentration approximately 50% of the maternal plasma concentration.
Son Güncelleme: 2017-04-26
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in de „enchytraeidae” die zich niet hebben ontlast, kan de concentratie van dit eerste monster van de eliminatiefase worden beschouwd als de weefselconcentratie na ontlasting van de darm.
in the non-purged enchytraeids, the concentration of this first sample of the elimination phase may be considered as the tissue concentration after gut purge.
Son Güncelleme: 2014-11-21
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de totale weefselconcentratie 24 uur na dosering in de epitheelvloeistof, alveolaire macrofagen, bronchiale mucosa, tonsillen en sinus weefsel bedroegen achtereenvolgens 0,84±0.65 mg/l, 162±96 mg/l, 0,78±0,39 mg/kg, 0,72±0,29 mg/kg en 1,58±1,68 mg/kg.
the total tissue concentration 24 h after dose in epithelial lining fluid, alveolar macrophages, bronchial mucosa, tonsils and sinus tissue were 0.84±0.65 mg/l, 162±96 mg/l, 0.78±0.39 mg/kg, 0.72±0.29 mg/kg and 1.58±1.68 mg/kg, respectively.
Son Güncelleme: 2017-04-26
Kullanım Sıklığı: 3
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