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de neurologische manifestaties worden als secundair beschouwd aan de abnormale stapeling van glycosfingolipiden in neuronale cellen en gliacellen.
the neurological manifestations are considered secondary to the abnormal accumulation of glycosphingolipids in neuronal and glial cells.
Son Güncelleme: 2017-04-26
Kullanım Sıklığı: 3
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de werking van zavesca is gebaseerd op het remmen van het enzym glucosylceramidesynthase dat verantwoordelijk is voor de eerste stap in de synthese van de meeste glycosfingolipiden.
zavesca works by inhibiting the enzyme called ‘glucosylceramide synthase’ which is responsible for the first step in the synthesis of most glycosphingolipids.
Son Güncelleme: 2017-04-26
Kullanım Sıklığı: 3
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als u aan de ziekte van niemann-pick type c lijdt, hopen vetten zoals glycosfingolipiden zich op in de cellen van uw hersenen.
if you have niemann-pick type c disease, fats such as glycosphingolipids build up in the cells of your brain.
Son Güncelleme: 2017-04-26
Kullanım Sıklığı: 3
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de ziekte van fabry is een stoornis van de opslag van glycosfingolipiden, veroorzaakt door een gebrekkige activiteit van het lysosomale enzym α -galactosidase a, die er toe leidt dat globotriaosylceramide (ook wel aangeduid als gb3 of cth), het glycosfingolipide substraat voor dit enzym, zich ophoopt.
fabry disease is a glycosphingolipid storage disorder that is caused by deficient activity of the lysosomal enzyme α -galactosidase a, resulting in accumulation of globotriaosylceramide (also referred to as gb3 or cth), the glycosphingolipid substrate for this enzyme.
Son Güncelleme: 2011-10-23
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