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det afviger kun ved unikke oligosaccharider i kulhydratdelen af molekylet.
mechanism of action xigris is a recombinant version of the natural plasma-derived activated protein c, from which it differs only by unique oligosaccharides in the carbohydrate portion of the molecule.
最后更新: 2011-10-23
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den gennemsnitlige molekylvægt er ca 60 kda, hvoraf proteindelen samt kulhydratdelen udgør ca.30 kda.
the average molecular mass is approximately 60 kda of which the protein moiety plus the carbohydrate part constitutes approximately 30 kda.
最后更新: 2008-03-04
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virkningsmekanisme xigris er en rekombinant udgave af det naturlige aktiverede protein c, som findes i plasma.det afviger kun ved unikke oligosaccharider i kulhydratdelen af molekylet.
mechanism of action xigris is a recombinant version of the natural plasma-derived activated protein c, from which it differs only by unique oligosaccharides in the carbohydrate portion of the molecule.
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methoxypolyethylenglycol-epoetin beta, det aktive stof i mircera, er en kontinuerlig erythropoetin receptoraktivator, der udviser en anderledes aktivitet på receptorniveau, og som har følgende karakteristika: en langsommere binding til og hurtigere adskillelse fra receptoren, en reduceret, specifik in vitro aktivitet med en forøget aktivitet in vivo, og desuden en forlænget halveringstid i modsætning til erythropoetin. den gennemsnitlige molekylvægt er ca 60 kda, hvoraf proteindelen samt kulhydratdelen udgør ca.30 kda..
methoxy polyethylene glycol-epoetin beta, the active ingredient of mircera, is a continuous erythropoietin receptor activator that shows a different activity at the receptor level characterized by a slower association to and faster dissociation from the receptor, a reduced specific activity in vitro with an increased activity in vivo, as well as an increased half-life, in contrast to erythropoietin.the average molecular mass is approximately 60 kda of which the protein moiety plus the carbohydrate part constitutes approximately 30 kda.
最后更新: 2008-03-04
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