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印尼语

diatas langit masih ada langit

英语

above the sky there is another sky

最后更新: 2021-04-12
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参考: 匿名

印尼语

apa ini masih ada

英语

这个还有吗

最后更新: 2022-02-19
使用频率: 1
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参考: 匿名

印尼语

selama persediaan masih ada

英语

applies multiply

最后更新: 2019-04-18
使用频率: 1
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参考: 匿名

印尼语

masih ada yang ditutupi dari saya

英语

the most potent suppressors of gastric acid secretion are inhibitors of the gastric h+,k+-atpase (proton pump) (figure 36–2a). in typical doses, these drugs diminish the daily production of acid (basal and stimulated) by 80% to 95%. five proton pump inhibitors are available for clinical use: omeprazole (prilosec, rapinex, zegerid) and its s-isomer, esomeprazole (nexium), lansoprazole (prevacid), rabeprazole (aciphex), and pantoprazole (protonix). these drugs have different substitutions on their pyridine and/or benzimidazole groups but are remarkably similar in their pharmacological properties (see appendix ii). omeprazole is a racemic mixture of r- and s-isomers; the s-isomer, esomeprazole (s-omeprazole), is eliminated less rapidly than r-omeprazole, which theoretically provides a therapeutic advantage because of the increased half-life. despite claims to the contrary, all proton pump inhibitors have equivalent efficacy at comparable doses. proton pump inhibitors are prodrugs that require activation in an acid environment. after absorption into the systemic circulation, the prodrug diffuses into the parietal cells of the stomach and accumulates in the acidic secretory canaliculi. here, it is activated by proton-catalyzed formation of a tetracyclic sulfenamide (figure 36–2), trapping the drug so that it cannot diffuse back across the canalicular membrane. the activated form then binds covalently with sulfhydryl groups of cysteines in the h+,k+-atpase, irreversibly inactivating the pump molecule. acid secretion resumes only after new pump molecules are synthesized and inserted into the luminal membrane, providing a prolonged (up to 24- to 48-hour) suppression of acid secretion, despite the much shorter plasma half-lives (0.5 to 2 hours) of the parent compounds. because they block the final step in acid production, the proton pump inhibitors are effective in acid suppression regardless of other stimulating factors. the most potent suppressors of gastric acid secretion are inhibitors of the gastric h+,k+-atpase (proton pump) (figure 36–2a). in typical doses, these drugs diminish the daily production of acid (basal and stimulated) by 80% to 95%. five proton pump inhibitors are available for clinical use: omeprazole (prilosec, rapinex, zegerid) and its s-isomer, esomeprazole (nexium), lansoprazole (prevacid), rabeprazole (aciphex), and pantoprazole (protonix). these drugs have different substitutions on their pyridine and/or benzimidazole groups but are remarkably similar in their pharmacological properties (see appendix ii). omeprazole is a racemic mixture of r- and s-isomers; the s-isomer, esomeprazole (s-omeprazole), is eliminated less rapidly than r-omeprazole, which theoretically provides a therapeutic advantage because of the increased half-life. despite claims to the contrary, all proton pump inhibitors have equivalent efficacy at comparable doses. proton pump inhibitors are prodrugs that require activation in an acid environment. after absorption into the systemic circulation, the prodrug diffuses into the parietal cells of the stomach and accumulates in the acidic secretory canaliculi. here, it is activated by proton-catalyzed formation of a tetracyclic sulfenamide (figure 36–2), trapping the drug so that it cannot diffuse back across the canalicular membrane. the activated form then binds covalently with sulfhydryl groups of cysteines in the h+,k+-atpase, irreversibly inactivating the pump molecule. acid secretion resumes only after new pump molecules are synthesized and inserted into the luminal membrane, providing a prolonged (up to 24- to 48-hour) suppression of acid secretion, despite the much shorter plasma half-lives (0.5 to 2 hours) of the parent compounds. because they block the final step in acid production, the proton pump inhibitors are effective in acid suppression regardless of other stimulating factors.

最后更新: 2014-04-24
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参考: 匿名

印尼语

berlaku selama persediaan masih ada

英语

while supplies last

最后更新: 2019-04-12
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参考: 匿名

印尼语

masih ada syarat yang harus dilengkapi

英语

there are still obstacles

最后更新: 2012-04-22
使用频率: 1
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参考: 匿名

印尼语

dia menjawab: "masih ada tambahan?"

英语

it will say, "are there any more (to come)?"

最后更新: 2014-07-03
使用频率: 2
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参考: 匿名
警告:包含不可见的HTML格式

印尼语

masih berada di episode menunggu

英语

masih berada di episode menunggu

最后更新: 2024-01-26
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参考: 匿名

印尼语

biarlah kita merendahkan diri dan menyerah, karena mungkin harapan masih ada

英语

he putteth his mouth in the dust; if so be there may be hope.

最后更新: 2012-05-06
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参考: 匿名

印尼语

dengarkanlah sebentar lagi, dan bersabarlah, masih ada yang hendak kukatakan demi allah

英语

elihu also proceeded, and said,

最后更新: 2012-05-06
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参考: 匿名

印尼语

wabah virus covid 19 masih ada saat ini, covid 19 awalnya berasal dari china

英语

the covid 19 virus outbreak still exists today, covid 19 originally came from china

最后更新: 2022-03-23
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参考: 匿名

印尼语

burung itu selalu terbang di atas langit setiap sore

英语

the bird always flies over the sky every afternoon

最后更新: 2023-02-22
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参考: 匿名

印尼语

pertandingan lain yang dijadwalkan hari rabu masih diadakan, menurut kantor berita nbc.

英语

other games scheduled for wednesday were still held, according to nbc news.

最后更新: 2020-08-25
使用频率: 1
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参考: 匿名

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