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hastigheden for ændringer i niveauet af biomarkører såsom calcitonin (ctn) og/eller carcinoembryonalt antigen (cea) samt hastigheden for forandringer i tumorvolumen under observation (watchful waiting) kan hjælpe med til at identificere ikke blot patienter med behov for behandlingen, men også det optimale tidspunkt for indledning af behandling med vandetanib.
rate of change in biomarker levels such as of calcitonin (ctn) and/or carcinoembryonic antigen (cea) as well as the rate of change of tumor volume during watchful waiting might help to identify not only patients in need for treatment but also the optimal moment to commence treatment with vandetanib.