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berperan penting
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koronavirus manusia oc43 selain menyebabkan infeksi pernapasan diduga juga berperan dalam penyakit neurologis.
human coronavirus oc43 besides causing respiratory infections is also suspected of playing a role in neurological diseases.

reseptor-reseptor ini mungkin juga berperan dalam keberhasilan adaptasi cov ini dalam manusia setelah transmisi antarspesies dari inang hewannya.
they might also account for successful adaptation of these covs in humans after interspecies transmission from their animal hosts.

protein orf3b sars-cov-2 mungkin berperan dalam patogenisitas virus dan inhibisi ekspresi ifnβ; namun, orf8 tidak memiliki domain fungsional atau motif yang dikenal.
the orf3b of sars-cov-2 may play a role in the viral pathogenicity and inhibit the expression of ifnβ; however, orf8 does not contain any known functional domain or motif.

di antara protein aksesori sars-cov, orf8 diduga berperan penting dalam adaptasi ke manusia sebab virus kelelawar kerabat-sars-cov yang diisolasi ditemukan menyandi beragam protein orf8.
among sars-cov accessory proteins, orf8 has been thought to be important in adaptation to humans, as sars-cov-related bat viruses were isolated but found to encode divergent orf8 proteins.

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