Results for fluoropyrimidinbehandling translation from Czech to English

anamnes på allvarliga eller oväntade reaktioner mot fluoropyrimidinbehandling,
history of severe and unexpected reactions to fluoropyrimidine therapy,

i denna studie randomiserades 627 patienter med metastaserad kolorektalcancer, som tidigare fått behandling med irinotekan i kombination med en fluoropyrimidinbehandling som första linjens terapi, till behandling med xelox eller folfox-4.
in this trial, 627 patients with metastatic colorectal carcinoma who have received prior treatment with irinotecan in combination with a fluoropyrimidine regimen as first line therapy were randomised to treatment with xelox or folfox-4.

hjärttoxicitet, inkluderande hjärtinfarkt, angina, arytmier, kardiogen chock, plötslig död och ekg- förändringar (inkluderande mycket sällsynta fall av qt-förlängning) har förknippats med fluoropyrimidinbehandling.
cardiotoxicity has been associated with fluoropyrimidine therapy, including myocardial infarction, angina, dysrhythmias, cardiogenic shock, sudden death and electrocardiographic changes (including very rare cases of qt prolongation).