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vedvarende brug kan medføre toleranceudvikling og hermed øget risiko for overdosering.
continuous use can lead to tolerance resulting in an increased risk of overdosing.
Last Update: 2012-04-12
Usage Frequency: 3
Quality:
langtidsbehandling med opioider fører typisk til toleranceudvikling over for de sekundære virkninger.
long-term treatment with opioids typically leads to development of tolerance to their secondary effects.
Last Update: 2012-04-12
Usage Frequency: 2
Quality:
efter subkutane injektioner med den samme dosis 4 gange med 48 timers mellemrum forbliver de biologiske responser forhøjet uden nogen tegn på toleranceudvikling.
after repeated subcutaneous administration every 48 hours for 4 doses, these biological responses remain elevated, with no signs of tolerance development.
Last Update: 2012-04-12
Usage Frequency: 2
Quality:
der er ikke observeret tab af krampestillende virkning (toleranceudvikling) ved kontinuerlig behandling i 4 uger i de eksperimentelle undersøgelser af fire ugers varighed.
no loss of anticonvulsant efficacy (tolerance development) during continuous treatment of 4 weeks was observed in experimental studies lasting 4 weeks.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
