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90. 000 gange lavere end corpus vitreum - ranibizumab koncentrationer.
serum ranibizumab concentrations are predicted to be approximately 90,000-fold lower than vitreal ranibizumab concentrations.
de serologiske test skal udføres på donorens serum eller plasma; de må ikke udføres på andre væsker eller sekreter såsom kammervand eller corpus vitreum.
the serological tests will be carried out on the donor’s serum or plasma; they should not be performed on other fluids or secretions such as the aqueous or vitreous humour.
på basis af en analyse af populationsfarmakokinetik og ranibizumabs forsvinden fra serum for patienter behandlet med dosen på 0, 5 mg er den gennemsnitlige corpus vitreum -eliminationshalveringstid for ranibizumab ca.
based on analysis of population pharmacokinetics and disappearance of ranibizumab from serum for patients treated with the 0.5 mg dose, the average vitreous elimination half-life of ranibizumab is
dexamethasonkoncentrationen forekom i faldende størrelsesorden i retina > iris > corpus ciliare > corpus vitreum > kammervand > plasma.
the rank order of dexamethasone concentration was retina > iris > ciliary body > vitreous humour > aqueous humour > plasma.
90. 000 gange lavere end corpus vitreum -ranibizumab koncentrationer.patienter med nyreinsufficiens:der er ikke udført formelle forsøg til undersøgelse af farmakokinetikken af lucentis hos patienter med nyreinsufficiens.
patients with renal impairment:no formal studies have been conducted to examine the pharmacokinetics of lucentis in patients with renal impairment.
injektionskanylen skal føres ind 3,5-4,0 mm posteriort for limbus i corpus vitreum-hulen, idet den horisontale meridian undgås, og der sigtes mod øjeæblets centrum.
the injection needle should be inserted 3.5-4.0 mm posterior to the limbus into the vitreous cavity, avoiding the horizontal meridian and aiming towards the centre of the globe.
vitrit, corpus vitreum-løsning, nethindeblødning, synsforstyrelse, øjensmerter, mouches volantes, konjunktival blødning, øjenirritation, fornemmelse af fremmedlegeme i øjnene, øget tåreflod, blefarit, tørt øje, okulær hyperæmi, øjenkløe.
vitritis, vitreous detachment, retinal haemorrhage, visual disturbance, eye pain, vitreous floaters, conjunctival haemorrhage, eye irritation, foreign body sensation in eyes, lacrimation increased, blepharitis, dry eye, ocular hyperaemia, eye pruritus.