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zowel cyp450 2d6 als cyp450 1a2 katalyseren de vorming van de twee belangrijkste metabolieten glucuronideconjugaat van 4-hydroxyduloxetine en sulfaatconjugaat van 5-hydroxy 6-methoxyduloxetine.
both cytochromes p450-2d6 and 1a2 catalyse the formation of the two major metabolites glucuronide conjugate of 4-hydroxy duloxetine and sulfate conjugate of 5-hydroxy 6-methoxy duloxetine.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
zowel cytochroom p450-2d6 als 1a2 katalyseren de vorming van de twee belangrijkste metabolieten glucuronideconjugaat van 4-hydroxyduloxetine en sulfaatconjugaat van 5- hydroxy,6-methoxyduloxetine.
both cytochromes p450-2d6 and 1a2 catalyse the formation of the two major metabolites glucuronide conjugate of 4-hydroxy duloxetine and sulphate conjugate of 5hydroxy,6-methoxy duloxetine.
Last Update: 2017-04-26
Usage Frequency: 7
Quality: