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English

tasimelteon 20 mg

Croatian

tazimelteon 20 mg

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

tasimelteon is extensively metabolised.

Croatian

tazimelteon se ekstenzivno metabolizira.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

the active substance is tasimelteon.

Croatian

djelatna tvar je tazimelteon.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

hetlioz 20 mg hard capsules tasimelteon

Croatian

hetlioz 20 mg tvrde kapsule tazimelteon

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

potential effect of alcohol on tasimelteon

Croatian

mogući utjecaj alkohola na tazimelteon

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

each hard capsule contains 20 mg tasimelteon.

Croatian

svaka tvrda kapsula sadrži 20 mg tazimelteona.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

each hard capsule contains 20 mg of tasimelteon.

Croatian

svaka tvrda kapsula sadrži 20 mg tazimelteona.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

race does not affect apparent clearance of tasimelteon.

Croatian

rasa ne utječe na prividni klirens tazimelteona.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

cyp2c19) in the metabolism of tasimelteon is unknown.

Croatian

cyp2c19) u metabolizmu tazimelteona nije poznata.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

potential for other medicinal products to affect tasimelteon

Croatian

mogućnost utjecaja drugih lijekova na tazimelteon

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

tasimelteon functions as a dmra at the mt1 and mt2 receptors.

Croatian

tazimelteon djeluje kao dmra na receptorima mt1 i mt2.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

there are no data on the effects of tasimelteon on human fertility.

Croatian

ne postoje podaci o učincima tazimelteona na plodnost u ljudi.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

it is unknown whether tasimelteon/metabolites are excreted in human milk.

Croatian

nije poznato izlučuje li se tazimelteon/metaboliti u majčino mlijeko u ljudi.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

tasimelteon exhibits a greater affinity for the mt2 as compared to the mt1 receptor.

Croatian

tazimelteon pokazuje veći afinitet za receptore mt2 u odnosu na receptore mt1.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

cyp1a2 and cyp3a4 are enzymes identified to play a role in the metabolism of tasimelteon.

Croatian

cyp1a2 i cyp3a4 su enzimi za koje je utvrđeno da imaju ulogu u metabolizmu tazimelteona.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

as a precautionary measure, it is preferable to avoid the use of tasimelteon during pregnancy.

Croatian

kao mjera opreza, preporučuje se izbjegavanje uporabe tazimelteona tijekom trudnoće.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

major metabolites had 13-fold or less activity at melatonin receptors compared to tasimelteon.

Croatian

glavni metaboliti imali su najmanje 13 puta manju aktivnost na receptorima melatonina u usporedbi s tazimelteonom.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

medicinal products that inhibit cyp1a2 and cyp3a4 have been shown to alter the metabolism of tasimelteon in vivo.

Croatian

pokazalo se da lijekovi koji inhibiraju cyp1a2 i cyp3a4 mijenjaju metabolizam tazimelteona in vivo.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

in pregnant rats administered tasimelteon during the period of organogenesis, there were no effects on embryofoetal development.

Croatian

u gravidnih štakora koji su tijekom organogeneze primali tazimelteon nije bilo utjecaja na embriofetalni razvoj.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

adverse reactions leading to discontinuation occurred in 2.3% of tasimelteon-treated patients.

Croatian

nuspojave koje su rezultirale prekidom uporabe lijeka zabilježene su kod 2,3 % bolesnika liječenih tazimelteonom.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

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